TTP, tritiated at C6. Tritiated TTP is used to make RNA probes or in other RNA polymerase assays. 3H probes can provide higher resolution compared to other isotopes.
1 mCi quantities of [6-3H]-Thymidine are available for your research. Application of [3H]Thymidine can be found in: carboxy-terminal PTH fragments stimulating incorporation in vascular endothelial cells, quantification of granulocyte-macrophage colony-stimulating factor (GM-CSF) hypersensitivity in juvenile myelomonocytic leukemia (JMML), influence of parasympathetic non-adrenergic, non-cholinergic mechanisms on uptake (rat) in response to mastication, measurement of dendritic cell induced T cell response by intracellular ATP levels and uptake in human immunology, etc.
Special Information: If aqueous solutions of thymidine are stored frozen (-20°C), care should be taken to protect the material from U.V. light during the thawing process to prevent possible dimerization.
When [methyl-3H]thymidine is incorporated into cellular DNA and undergoes radiolytic decomposition, [3H]5-hydroxymethyl-2''-deoxyuridine (HMdU) is formed.* The formation of HMdU through transmutation of [methyl-3H]thymidine occurs at the rate of B-decay, which is 0.017% per day. The transmutation product is not volatile.
*References
Molecular Weight |
242.2
|
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Application |
Molecular Biology
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Brand |
NEN Radiochemicals
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Detection Method |
Radiometric
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Label Position |
Specifically Labeled
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Radionuclide |
3H
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Radioisotope |
H-3
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Shipping Conditions |
Shipped Ambient
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Special Ordering Information |
This is a radioactive product - shipping address must have a license to receive radioactive materials.
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Unit Size |
1 mCi
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