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Ryanodine, [9,21-3H(N)]-, 250µCi (9.25MBq)

Ryanodine, tritiated at the 9,21 position. Ryanodine is a natural ligand for the ryanodinen receptor.

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Part Number List Price Your Price Quantity
NET950250UC 3230.00 EUR
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Ryanodine is a plant alkaloid and natural ligand for the ryanodinen receptor (RyR), a class of calcium channels (Ca2+ channels).

We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.

Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NET950:

  1. Araki, T., Kato, H., Shuto, K., Oshima, Y. and Itoyama, Y. (1998), Postischemic changes of [3H]nimodipine and [3H]ryanodine binding in the gerbil striatum and hippocampus. European Journal of Neurology, 5: 195–201.


Concentration <1.0 mCi/mL
Detection Method Radiometric
Label Position Nominally Labeled
Molecular Weight 493.5
Product Brand Name NEN Radiochemicals
Radioisotope H-3
Radionuclide 3H
Receptor Type Calcium
Shipping Condition Dry Ice
Special Ordering Information This is a radioactive product - shipping address must have a license to receive radioactive materials.
Therapeutic Area CNS & Neurologic, Musculoskeletal
Unit Size 250 µCi