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IVIS Lumina XRMS In Vivo Imaging System

Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.

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The Lumina XRMS includes state of the art spectral unmixing for sensitive multispectral imaging to monitor multiple biological events in the same animal. Use our Living Image® software to automate all the controls and settings required for seamless image acquisition and processing. Typical X-ray image acquisitions take only 10 seconds and can be overlaid with both optical and photographic images.

Superior Optical Imaging with Spectral Unmixing

The IVIS Lumina XRMS Series III is capable of imaging all common fluorescent and bioluminescent reporters or dyes. The system is equipped with up to 21 filter sets to image reporters that emit from green to near-infrared. High resolution, sharp cut-off filters are simply interchangeable to achieve the highest performance, sensitivity and spectral unmixing. The Lumina XRMS imaging system also accommodates Petri dishes or micro-titer plates for in vitro imaging.

The system can incorporate premium animal handling features such as a heated stage, gas anesthesia connections and a syringe injection system for simultaneous compound administration. Living Image software yields high-quality, reproducible, quantitative results incorporating instrument calibration, background subtraction and the image algorithms. Simple user guided spectral unmixing allows detection and separation of multiple reporters, and Living Image provides the precise overlay to see your optical reporters together with anatomical surface or X-ray features.

Features and Benefits:

  • Multispecies optical and X-ray imaging
  • Image mice, rats and other large animals
  • High resolution, low dose digital X-Ray
  • Exquisite sensitivity in bioluminescence
  • Compute Pure Spectrum (CPS) spectral unmixing for ultimate fluorescence sensitivity
  • Full fluorescence tunability through the NIR Spectrum

Disclaimer:  For research use only. Not for use in diagnostic procedures.


Imaging Modality Optical Imaging
Optical Imaging Classification Bioluminescence imaging, Fluorescence Imaging
Portable No
Product Brand Name IVIS

Resources, Events & More

All (25)
Resource Type File Name File Format
Product Note IVIS Lumina XRMS Series III (Product Note) PDF  2 MB
Product Note RAS-4 Rodent Anesthesia System PDF  562 KB
Application Note Cerenkov Imaging of Radioisotopes in IVIS systems PDF  2 MB
Application Note Stem Cell Research and Regenerative Medicine PDF  1 MB
Technical Note Adaptive Fluorescence Background Subtraction PDF  1 MB
Technical Note AutoExposure PDF  1 MB
Technical Note Background ROI PDF  1 MB
Technical Note Determine Saturation PDF  1 MB
Technical Note Drawing ROIs PDF  669 KB
Technical Note High Resolution Images PDF  1 MB
Technical Note Image Overlay 2D PDF  472 KB
Technical Note Loading Groups of Images PDF  751 KB
Technical Note Subject ROI PDF  2 MB
Technical Note Working with Image Math PDF  911 KB
Technical Note Working with Imaging Wizard PDF  4 MB
Featured Publication Note Imaging in CRISPR/Cas9 Applications PDF  443 KB
Flyer Comparison of IVIS Imaging Systems PDF  1 MB
Citations Library View peer reviewed publications using PerkinElmer's In Vivo Imaging systems Link
Software Downloads In Vivo Imaging Software Downloads Link
Video Article JoVE Video Articles Link
Webinars In Vivo Imaging: Advancing Preclinical and Translational Science in Molecular and Orthopedic Research at UCLA - View On Demand Link
Webinars In Vivo Imaging Today and Tomorrow: How multimodal imaging is driving translational research - View On Demand Link
Webinars View our complete list of in vivo webinars available on demand Link
Webinars Optical and microCT Imaging of Bacteria, Viruses, and Tumors - View On Demand Link
Webinars Application of Cerenkov Luminescence for Brown Adipose Tissue Imaging and In vivo Photochemistry - View On Demand Link