PerkinElmer
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GLP-1 (7-36), [125I]-, 10µCi (370kBq)

Glucagon-like peptide-1 (GLP-1), labeled with 125I. GLP-1 is a peptide hormone involved in secretion of insulin, and binds and activates GLP-1 receptors, a member of the glucagon receptor family of GPCRs.

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Unit Size
List Price
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Quantity
NEX308010UC
10 µCi
1501.00 EUR
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NEX308050UC
50 µCi
2739.00 EUR
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Detail Information

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX308:

  1. Wallrapp, C., Thoenes, E., Thürmer, F., Jork, A., Kassem, M., Geigle, P. (2013), Cell-based delivery of glucagon-like peptide-1 using encapsulated mesenchymal stem cells. J MIcroencapsul, 30 (4): 315-324.

Specifications

Concentration 83.8 µCi/mL
Detection Method Radiometric
Fresh Lot Days First Monday of each month
Label Position Nominally Labeled
Product Brand Name NEN Radiolabeled Ligands
Radioisotope I-125
Radionuclide 125I
Receptor Type Glucagon
Shipping Condition Dry Ice
Special Ordering Information This is a radioactive product - shipping address must have a license to receive radioactive materials.
Therapeutic Area Gastrointestinal
Unit Size 10 µCi