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Batrachotoxinin A 20-α-Benzoate, [Benzoyl-2,5-3H]-, 100µCi (3.7MBq)

Batrachotoxinin A 20-α-Benzoate, [Benzoyl-2,5-3H]- acts as a ligand for voltage-dependent sodium channels.

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Detail Information

Batrachotoxinin A 20-alpha-benzolate (BTX-B) binds sodium channels in the brain and is used to study effects of local anesthetic drugs.

We offer both agonist and antagonist radioligands for autoradiographic visualization or performing saturation and competition assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radioligands is fully characterized for pharmacological action and validated in receptor binding assays.

Radiolabeled ligands remain the most sensitive method for probing receptor binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NET876:

  1. Grima, M., Schwartz, J., Spach, M.O. and Velly, J. (1986), Anti-anginal arylalkylamines and sodium channels: [3H]-batrachotoxinin-A 20-α-benzoate and [3H]-tetracaine binding. British Journal of Pharmacology, 89: 641–646.
  2. Petrus J. Pauwels, Josee E. Leysen, Pierre M. Laduron. (1986), [3H]Batrachotoxinin a 20-α-benzoate binding to sodium channels in rat brain: Characterization and pharmacological significance, In European Journal of Pharmacology, Volume 124, Issue 3, Pages 291-298.


Concentration 1.0 - 10 mCi/mL
Detection Method Radiometric
Fresh Lot Days To be determined
Label Position Specifically Labeled
Molecular Weight 521.7
Product Brand Name NEN Radiochemicals
Radioisotope H-3
Radionuclide 3H
Receptor Type Sodium
Shipping Condition Dry Ice
Special Ordering Information This is a radioactive product - shipping address must have a license to receive radioactive materials.
Therapeutic Area CNS & Neurologic
Unit Size 100 µCi