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α-Dendrotoxin [125I] 5 µCi

NEX434 [125I]- α-Dendrotoxinsare a class of neurotoxins produced by mamba snakes that block particular subtypes of voltage-gated potassium channels in neurons. Dendrotoxins enhance the release of acetylcholine at neuromuscular junctions.

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NEX434005UC
5 µCi
1297.00 EUR
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NEX434010UC
10 µCi
2067.00 EUR
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Detail Information

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

Specifications

Detection Method Radiometric
Fresh Lot Days Fourth Monday of each Month
Label Position Nominally Labeled
Molecular Weight 7000.0
Product Brand Name NEN Radiolabeled Ligands
Radioisotope I-125
Radionuclide 125I
Receptor Type Potassium
Shipping Condition Ambient
Special Ordering Information This is a radioactive product - shipping address must have a license to receive radioactive materials.
Therapeutic Area CNS & Neurologic
Unit Size 5 µCi