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Genhance on the ASK


Overview


Genhance™ agents are small molecule fluorescent agents that can be used as a control or in vascular permeability imaging/blood pooling. Genhance enables imaging of circulation, blood vessels, and the vasculature. It is typically imaged using intravital microscopy (IVM). Genhance™ 680 is the acid form of VivoTag® 680 and Genhance™ 750 is the acid form of VivoTag® 750. Both agents come in two sizes (1 mg and 5 mg).


Products and catalog numbers


ProductCatalog NumberEx/Em wavelength (nm)Molecular weight (g/mol)Validated ExperimentsApplicationsStorage and Stability
Genhance 680
(1 mg)
NEV10117670/688~ 1646In vivoControl
Vascular
Technical Data Sheet
Genhance 680
(5 mg)
NEV10130670/688~ 1646In vivoControl
Vascular
Technical Data Sheet
Genhance 750
(1 mg)
NEV10118750/7751086In vivoControl
Vascular
Technical Data Sheet
Genhance 750
(5 mg)
NEV10177750/7751086In vivoControl
Vascular
Technical Data Sheet


Using Genhance in vivo


GenhanceRoute of InjectionMouse Dose (25 g)Rat Dose (250 g)Blood t 1/2Tissue t 1/2Optimal imaging timeOptimal Re-injection Time (complete clearance)Route of Metabolism/ background tissueFMT& IVIS settings
Genhance 680IV50 ug150-500 ug0.5 hnot determined0.5 hnot determinedBladderFMT 680/700
IVIS 675/720
Genhance 750IV50 ug150-500 ug0.5 hnot determined0.5 hnot determinedBladderFMT 750/770
IVIS 745/800


Citations


Please visit our Citations Library for references using Genhance on the IVIS or on the FMT.