PerkinElmer

Receptor Ligand Binding

OF

Simplify the development of your assays and the calculation of your results using our radioligands, receptor-transfected cell membranes, and cell lines for radioligand binding applications.

Because radioligands can be directly detected, there is no need to generate intermediate antibodies against your target. Eliminating these antibodies also eliminates the need to optimize an antibody titer and reduces your total assay time by skipping intermediate incubation steps.

You’ll find our receptor-ligand binding reagents and related products perfect matches for all of your receptor binding studies.

 

  • Products and Services

  • Resources, Events & More

Narrow your results
Product Type
  • Reagents (761)
  • Consumables (11)
  • Instruments (7)
Application
  • Drug Discovery & Development (536)
  • cAMP (26)
  • Molecular Biology (2)
  • Protein Analysis & Detection (2)
  • Protein-protein interactions (2)
  • Plant Sciences (1)
Assay Target Class
  • GPCR (181)
  • Transporter (6)
  • Ion channel (3)
  • Tyrosine Kinase Receptor (1)
Assay Validated
  • Binding (214)
  • cAMP (56)
  • GTPγS (52)
  • Calcium Fluorescence (20)
  • Inositol Phosphate (15)
  • Downstream Phosphorylation (1)
Automation Compatible
  • Yes (40)
  • No (22)
Coating Treatment
  • WGA (23)
  • PEI (19)
  • Streptavidin (15)
  • Poly-lysine (8)
  • Protein A (6)
  • Glutathione (6)
  • PDE (3)
  • Anti-rabbit IgG (3)
  • Poly-L-lysine (3)
  • Membrane-binding (3)
  • Copper (HIS-tag) (2)
  • Copper chelate (2)
  • Anti-mouse IgG (2)
  • Nickel chelate (HIS-tag) (2)
  • Anti-mouse antibody (2)
  • HIS (2)
  • Anti-rabbit antibody (2)
  • RNA Binding (1)
  • Arginine-binding (1)
  • Anti-sheep antibody (1)
  • Anti-sheep IgG (1)
  • WGA PEI type A (1)
  • WGA PEI Type B (1)
  • Uncoated (1)
  • Neomycin (1)
Color
  • White (4)
Concentration
  • 1.0 - 10 mCi/mL (92)
  • <1.0 mCi/mL (12)
  • 1 mCi/mL (6)
  • 353 µCi/mL (5)
  • <1.0 µCi/mL (4)
  • 345 µCi/mL (4)
  • 1.0 - 10 µCi/mL (3)
  • 41.4 µCi/mL (3)
  • 172.5 µCi/mL (3)
  • 236 µCi (3)
  • 1.12 mCi/mL (2)
  • 171.9 µCi/mL (2)
  • 182 µCi/mL (2)
  • 93.2 µCi/mL (2)
  • 170.1 µCi/mL (2)
  • 45.7 µCi/mL (2)
  • 2.93 MBq/mL (2)
  • 33.7 µCi (2)
  • <100 µCi/mL (2)
  • 79.2 µCi/mL (2)
  • 6.05 MBq/mL (1)
  • 87.2 µCi/mL (1)
  • 88.5 µCi/mL (1)
  • 173.9 µCi/mL (1)
  • 171 µCi/mL (1)
  • 3.22 MBq/mL (1)
  • 1.14 mCi/mL (1)
  • 13.3 MBq/mL (1)
  • 85.1 µCi/mL (1)
  • 42.5 µCi/mL (1)
  • 152 µCi/mL (1)
  • 87.6 µCi/mL (1)
  • 50 µCi/mL (1)
  • 87.4 µCi/mL (1)
  • 86.3 µCi (1)
  • 83.8 µCi/mL (1)
  • 87.9 µCi/mL (1)
  • 3.06 MBq/mL (1)
  • 2 mCi/mL (1)
  • 1.0 mCi/mL (1)
Detection Method
  • Radiometric (485)
  • DELFIA TRF (4)
  • Filtration (4)
  • Time-Resolved Fluorescence (TRF) (4)
  • Fluorescence (1)
Experimental type
  • In vitro (4)
Fluorophore
  • 5-FAM (28)
  • FITC (3)
  • Eu-N1-ITC (2)
Format
  • Microplates (38)
  • Tubes (30)
Host Cell
  • CHO-K1 (132)
  • HEK293 (38)
  • 1321N1 (13)
  • MDCK (2)
  • A431 (1)
  • MDA-MB-435S (1)
  • A9 (1)
  • UC11 (1)
  • Balb 3T3 (1)
  • IMR-32 (1)
  • U373 (1)
  • L Cells (1)
  • K562 (1)
  • CHO-DHFR(-) (1)
  • HT29 (1)
Label Position
  • Nominally Labeled (210)
  • Specifically Labeled (186)
  • Generally Labeled (10)
  • Uniformly Labeled (1)
Material
  • Barex/GF/B (1)
  • Barex/GF/C (1)
  • Polystyrene/GF/B (1)
  • Polystyrene/GF/C (1)
Number of Wells
  • 96 (4)
Product Brand Name
  • NEN Radiochemicals (222)
  • NEN Radiolabeled Ligands (178)
  • Membrane Target Systems (119)
  • ValiScreen (75)
  • SPA Scintillation Beads (30)
  • SPA Imaging Beads (22)
  • UniFilter (7)
  • DELFIA (4)
  • MicroBeta (2)
  • LabChip® (1)
  • OmniFilter (1)
  • cAMPZen (1)
Radionuclide
  • 3H (209)
  • 125I (180)
  • 14C (13)
  • 33P (2)
  • 35S (2)
Radioisotope
  • H-3 (213)
  • I-125 (181)
  • C-14 (12)
  • P-33 (2)
  • S-35 (2)
Receptor Type
  • Dopamine (35)
  • Opioid (25)
  • 5-Hydroxytryptamine (Serotonin) (23)
  • Chemokine (21)
  • Adrenoceptors (21)
  • 5-Hydroxytryptamine (21)
  • Nicotinic (18)
  • Acetylcholine (Muscarinic) (18)
  • Melanocortin (17)
  • Adenosine (17)
  • Vasopressin (16)
  • GABAA (14)
  • Benzodiazepine (13)
  • Adrenergic (13)
  • Somatostatin (13)
  • Glutamate (13)
  • Histamine (12)
  • Calcium (11)
  • Tachykinin (11)
  • Angiotensin (10)
  • Muscarinic (10)
  • Cannabinoid (10)
  • Glucagon (10)
  • Prostanoid (8)
  • Bombesin (8)
  • Neurotensin (8)
  • Serotonin (8)
  • Neuropeptide (7)
  • Calcitonin (7)
  • Neuropeptide Y (6)
  • Cholecystokinin (6)
  • Thyroid Hormone (6)
  • Vasoactive Intestinal Peptide (5)
  • hERG (5)
  • Endothelin (5)
  • Insulin (5)
  • Glycine (5)
  • Galanin (5)
  • Ghrelin (5)
  • Epidermal Growth Factor (5)
  • Interleukin (4)
  • Dopamine Transporter (4)
  • Oxytocin (4)
  • Melatonin (4)
  • Apelin (4)
  • GABA (4)
  • Bradykinin (4)
  • Anaphylatoxin (4)
  • Neuromedin U (3)
  • Peptide P518 (3)
  • Corticotropin-Releasing Factor (3)
  • Orexin (3)
  • Urotensin (3)
  • Leukotriene (3)
  • Potassium (3)
  • Relaxin (3)
  • Transforming Growth Factor (3)
  • SK channels (2)
  • Motilin (2)
  • Sodium (2)
  • Gonadotropin-releasing Hormone (2)
  • Thyrotropin-releasing Hormone (2)
  • Purinergic P2Y (2)
  • Melanin-Concentrating Hormone (2)
  • Growth Hormone (2)
  • Free Fatty Acid (2)
  • Insulin-like Growth Factor (2)
  • Norepinephrine (2)
  • Prolactin Releasing Peptide (2)
  • Thyrotropin Releasing Hormone (2)
  • Formyl Peptide (2)
  • GABAB (2)
  • Progestin (1)
  • NMDA (1)
  • TRPC5 (1)
  • Acetylcholine (1)
  • SVCT1 (1)
  • Metastin (1)
  • Platelet-Derived Growth Factor (1)
  • SVCT2 (1)
  • Norephinephrine (1)
  • Vesicular Amine Transporters (VATs) (1)
  • Prokineticin (1)
  • Retinoic Acid Receptors (1)
Sample Volume
  • 35 mL (1)
  • 2 mL (1)
  • 400 mL (1)
Target Species
  • Human (6)
Therapeutic Area
  • CNS & Neurologic (252)
  • Inflammation (200)
  • Cardiovascular (166)
  • Pain (112)
  • Gastrointestinal (105)
  • Central Nervous System (101)
  • Metabolic Disorders (79)
  • Metabolic (54)
  • Cancer (42)
  • Angiogenesis (34)
  • Diabetes (29)
  • Obesity (15)
  • Parasympathetic Nervous System (5)
  • Immune (3)
  • Sympathetic Nervous System (2)
  • Renal (2)
  • Musculoskeletal (1)
Volume
  • 0-50 (274)
  • 201-250 (120)
  • 351-400 (82)
  • 51-100 (9)
  • 451-500 (3)

"Receptor Ligand Binding" 1-50 of 779 Products and Services

Sort
Per Page

OMNIFILTER-96 CELL HARVESTER

Speed and simplicity are the primary strengths of the OmniFilter Harvester.
LabChip EZ Reader

EZ READER, SHIP LEVEL

The EZ Reader can help to save time and money in your laboratory by identifying the most promising lead candidates faster.

UNIFILTER-96 CELL HARVESTER

Speed and simplicity are the primary strengths of the Unifilter Harvester.

MICROBETA FILTERMAT-96 CELL HARVESTER

Speed and simplicity are the primary strengths of the FilterMate Harvester. From beginning to end, the FilterMate system is easy to use.

UNIFILTER-96 CELL HARVESTER SS

Speed and simplicity are the primary strengths of the Unifilter Harvester.

MICROBETA FILTERMAT-24 CELL HARVESTER

Speed and simplicity are the primary strengths of the FilterMate Harvester. From beginning to end, the FilterMate system is easy to use. Need additional information? Click on the tabs in the product details section below.

UNIFILTER-24 CELL HARVESTER

Speed and simplicity are the primary strengths of the Unifilter Harvester.

Ghrelin (human), [His[125I]], 10µCi

NEX388 Ghrelin is an acylated endogenous peptide which stimulates the release of growth hormone from the pituitary through an orphan G-protein-coupled receptor (GHS-R)7. Ghrelin is an appetite inducing hormone produced in the stomach and the upper portion of the small intestine. [ [125I]His ]Ghrelin (human), binds to GHS-R with high affinity.
List Price : 1583.00 EUR
PerkinElmer

Membrane Target Systems: Urotensin UR2 (GPR14) (mouse) membrane preparation

Cell membranes prepared from cells stably-transfected with human Urotensin UR2 (GPR14) receptor, in CHO-K1 cells.
List Price : 784.00 EUR
PerkinElmer

Membrane Target Systems: Serotonin 5HT3 (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Serotonin 5-HT3 receptor, in HEK-293 cells.
List Price : 784.00 EUR

Lysergic Acid Diethylamide, 2-[125I]iodo-(+), 10µCi

NEX199 Preparations have been shown to be active in binding to the serotonin receptors. LSD affects a large number of the G protein coupled receptors, including all dopamine receptor subtypes, and all adrenoreceptor subtypes, as well as many others. LSD binds to most serotonin receptor subtypes except for 5-HT3 and 5-HT4.
List Price : 1032.00 EUR

EPOXYCHOLESTEROL, 24(S),25-[26,27-(3H)]-, 100 µCi

Note: This product will be discontinued from our catalog portfolio on January 1, 2017.
List Price : 3769.00 EUR
PerkinElmer

Membrane Target Systems: Muscarinic M3 (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Muscarinic M3 receptor, in CHO-K1 cells.
List Price : 784.00 EUR
PerkinElmer

STREP PVT SPECIAL 25 X 500 MG

Streptavidin-coated SPA beads, for capturing biotinylated biomolecules in proximity-based radiometric scintillation assays.
List Price : 60700.00 EUR
PerkinElmer

Membrane Target Systems: Cannabinoid CB1 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 784.00 EUR
PerkinElmer

ValiScreen Muscarinic M5 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
PerkinElmer

ValiScreen Leukotriene BLT1 (LTB4R1) (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.

ProTx-II (tarantula), [125I], 10µCi

[125I]-ProTx-II (tarantula) NEX450010UC. This product extends offerings for sodium Ion channels, the disease state is Pain. ProTx-II selectively alters the rate of activation for voltage-gated sodium channels Nav1.7. Related products Sodium Channel and Potassium Channel
List Price : 1225.00 EUR
PerkinElmer

Streptavidin PS 2G Imaging Beads

Streptavidin-coated SPA beads, for capturing biotinylated molecules in proximity-based scintillation assays.
List Price : 4932.00 EUR

U-69,593, [Phenyl-3,4-3H]-, 25µCi (925kBq)

25 µCi quantities of [Phenyl-3, 4-3H]-U-69,593 are available for your research.
List Price : 926.00 EUR
PerkinElmer

ValiScreen Neuropeptide Y Y2 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.

Iodoaminopotentidine, [125I], 25 µCi

NEX431 [125I]-Aminopotentidine has been shown to work in receptor binding and autoradiography and is an antagonist for histamine (H2) receptors.
List Price : 2264.00 EUR
PerkinElmer

ValiScreen Serotonin 5HT-5A (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
PerkinElmer

Membrane Target Systems: A9 cells membranes

Wild Type Subtype A9L (mouse) Control Membrane 10mg Frozen suspension cell membrane. Shipped on dry ice.
List Price : 467.00 EUR
List Price : 1366.00 EUR

DTG (1,3-Di-o-tolylguanidine, [p-ring-3H]-), [5-3H(N)]-, 250µCi (9.25MBq)

250 µCi quantities of [5-3H(N)]-DTG (1, 3-Di-o-tolylguanidine, [p-ring-3H]-) are available for your research.
List Price : 2909.00 EUR

Insulin (human, recombinant), [125I], 50 µCi

[125I]-Insulin (h) is suitable for the use in radioimmunoassay as well as receptor binding assay. [125I]-Insulin (h) is radioiodinated with no carrier added 125I using the LPO iodination procedure and is purified by reversed phase HPLC.
List Price : 2477.00 EUR

Spiperone (Spiroperidol), [Benzene ring-3H]-, 250µCi (9.25MBq)

250 µCi quantities of [Benzene ring-3H]-Spiperone (Spiroperidol) are available for your research.
List Price : 2193.00 EUR
PerkinElmer

Streptavidin PS Imaging Beads 500 MG

Streptavidin-coated SPA beads, for capturing biotinylated molecules in proximity-based scintillation assays.
List Price : 1235.00 EUR

Sauvagine, [125I]-Tyr0], 50µCi

NEX306 [125I]Tyr0-Sauvagine has been shown to be active in receptor binding assays and has been used for receptor autoradiography.
List Price : 2538.00 EUR
PerkinElmer

ValiScreen Bombesin BB2 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
PerkinElmer

Copper HIS-Tag YSI 125MG

SPA (scintillation proximity assay) beads designed for the capture of His-tagged proteins and peptides.
List Price : 710.00 EUR

Oxytocin, [Tyrosyl-2,6-3H]-, 50µCi (1.85MBq)

50 µCi quantities of [Tyrosyl-2, 6-3H]-Oxytocin are available for your research.
List Price : 1393.00 EUR

Sphingosine-1-phosphate, 33P

Sphingosine-1-phosphate is a bioactive lipid and can be used as an endogenous ligand in sphingosine-1-phosphate (S1P) receptor binding assays.
Price Range : 17100.00 EUR - 42200.00 EUR

Methylhistamine Dihydrochloride, N-α-[methyl-3H]-, 250µCi (9.25MBq)

250 µCi quantities of tritiated methylhistamine dihydrochloride are available for your research.
List Price : 1184.00 EUR

Iodoaminopotentidine, [125I], 10 µCi

NEX431 [125I]-Aminopotentidine has been shown to work in receptor binding and autoradiography and is an antagonist for histamine (H2) receptors.
List Price : 1003.00 EUR
PerkinElmer

ProfilerPro Kinase Peptide Substrate 21, for LabChip EZ Reader

Fluorescently-labelled peptide substrate 21 for kinase assays (inhibiton, target discovery, lead optimization)
List Price : 665.00 EUR
PerkinElmer

Membrane Target Systems: Serotonin 5HT6 (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Serotonin 5-HT6 receptor, in HEK-293 cells.
List Price : 784.00 EUR

(+)-Pentazocine, [Ring-1,3-3H]-,250µCi (9.25MBq)

250 µCi quantities of [Ring-1, 3-3H]-(+)-Pentazocine are available for your research.
List Price : 2710.00 EUR
PerkinElmer

Membrane Target Systems: Adenosine A3 (rat) membrane preparation

Cell membranes prepared from cells stably-transfected with rat Adenosine A3 receptor, in HEK-293 cells.
List Price : 784.00 EUR
PerkinElmer

Membrane Target Systems: Epidermal Growth Factor Receptor EGF membrane preparation

Cell membranes prepared from A431 cells containing human endogenous EGF receptor.
List Price : 784.00 EUR

Iodo-Melatonin, 2-[125I], 100µCi

NEX236 2-[125I]-iodomelatonin has been used to identify, characterize and localize melatonin binding sites in the brain and peripheral tissues.
List Price : 1890.00 EUR
List Price : 2120.00 EUR
PerkinElmer

ValiScreen Somatostatin sst2a (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.

Muscimol, 3-Hydroxy-5-Aminomethylisoxazole, [Methylene-3H(N)]-, 1mCi (37MBq)

1 mCi quantities of [Methylene-3H(N)]-Muscimol are available for your research.
List Price : 5900.00 EUR

Pirenzepine, [N-Methyl-3H]-, 1mCi (37MBq)

1 mCi quantities of [N-Methyl-3H]-Pirenzepine are available for your research.
List Price : 6300.00 EUR
PerkinElmer

Membrane Target Systems: Ghrelin Ghrelin (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Ghrelin receptor, in HEK-293 cells.
List Price : 784.00 EUR

VINBLASTINE SULPHATE, [G-3H]

50 µCi quantities of [G-3H]-Vinblastine Sulphate are available for your research.
List Price : 2012.00 EUR
PerkinElmer

ProfilerPro Kinase Peptide Substrate 11, for LabChip EZ Reader

Fluorescently-labelled peptide substrate 11 for kinase assays (inhibiton, target discovery, lead optimization)
List Price : 665.00 EUR

Diprenorphine [15,16-3H]-, 25µCi (925kBq)

25 µCi quantities of [15, 16-3H]-Diprenorphine are available for your research.
List Price : 798.00 EUR

"Receptor Ligand Binding" 1-50 of 779 Products and Services

Per Page