PerkinElmer

Protein-protein Interaction Research

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Protein-protein interaction research is uncovering new targets for drug discovery in cancer and a variety of other diseases. However, measurement, modulation, and detection of protein-protein interaction is challenging, and requires technology capable of measuring both high- and low-affinity interactions.

The full measurement capabilities of our protein-protein interaction analysis technologies include:

  • Transient and stable interactions
  • Low-to-high affinity interactions (pM to mM affinity)
  • Full-length protein-protein binding
  • Peptide-protein
  • Receptor dimerization
  • Protein-small molecule
  • Protein complex interactions

Modulation of protein interactions can affect signal transduction, growth factor, gene expression, and other factors, making it a promising new avenue for protein-based treatment.

Development of protein-based therapeutics requires a thorough understanding of protein function and interactions. Our protein-protein interaction assays and instruments allow fast, multilabel detection of protein-protein interaction for drug discovery.

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Product Type
  • Accessories (4)
  • Instruments (6)
  • Reagents (109)
Antibody Conjugates
  • Anti-6X His (7)
  • Anti-bovine IgA (1)
  • Anti-c-Myc (4)
  • Anti-C-tag (3)
  • Anti-DIG (2)
  • Anti-DNP (2)
  • Anti-FITC (3)
  • Anti-FLAG (6)
  • Anti-GFP (2)
  • Anti-goat IgG (1)
  • Anti-GST (5)
  • Anti-HA (4)
  • Anti-HRP (2)
  • Anti-human IgG (3)
  • Anti-MBP (1)
  • Anti-mouse IgG (3)
  • Anti-rabbit IgG (2)
  • Anti-rat IgG (2)
  • Anti-V5 (3)
  • Glutathione (3)
  • Nickel chelate (1)
  • Protein A (5)
  • Protein G (1)
  • Protein L (1)
  • Strep-Tactin (1)
  • Streptavidin (11)
  • Streptavidin/Anti-c-Myc (1)
  • Streptavidin/Anti-DIG (1)
  • Streptavidin/Anti-FITC (1)
  • Streptavidin/Anti-FLAG (1)
  • Streptavidin/Anti-GST (1)
  • Streptavidin/Anti-HA (1)
  • Streptavidin/Anti-mouse IgG (1)
  • Streptavidin/Anti-rabbit IgG (1)
  • Streptavidin/Nickel chelate (1)
  • Streptavidin/Protein A (1)
  • Unconjugated (2)
Application
  • Antibody binding (1)
  • Enzymatic (5)
  • Isotyping (1)
  • Multiplexing (2)
  • Protein Analysis & Detection (51)
  • Protein-nucleic acid interactions (4)
  • Protein-protein interactions (94)
Assay points(200-50,000)
  • 100 (5)
  • 10000 (11)
  • 500 (25)
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  • 50000 (10)
Assay Target
  • COX-2 (2)
  • EGF (2)
  • EGFR (3)
  • FCGR1 (1)
  • FCGR2A (2)
  • FCGR2B (1)
  • FCGR3A (2)
  • Histone H4 (2)
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  • PD-L1 (2)
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  • Fc-receptor (6)
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  • Protein (8)
Automation Compatible
  • Yes (112)
Detection Method
  • Absorbance (5)
  • Alpha (67)
  • DELFIA TRF (7)
  • Fluorescence (5)
  • Fluorescence Polarization (3)
  • Image-based Cytometry (1)
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  • Time-Resolved Fluorescence (TRF) (31)
  • TR-FRET (19)
Experimental Type
  • In vitro (78)
Fluorophore
  • Eu-N1 (5)
  • Eu-W1024 (9)
  • Eu-W8044 (1)
  • Sm-N1 (1)
  • SureLight APC (4)
  • Tb-N1 (1)
  • ULight (8)
Format
  • Microplates (84)
Maximum Temperature (Celsius)
  • 40-50 (2)
  • 50-60 (2)
Molecular Modification
  • Acetylation (2)
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  • Alpha (6)
  • AlphaLISA (42)
  • AlphaPlex (16)
  • AlphaScreen (12)
  • DELFIA (7)
  • EnSight (1)
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  • Victor (1)
  • ViewLux (1)
Target Species
  • Human (9)
  • Mouse (1)
Therapeutic Area
  • Biologics/Bioprocess (6)
  • Cancer (8)
  • Epigenetics (2)

"Protein-protein Interaction Research" 1-50 of 119 Products and Services

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EnSight multimode plate-reader

EnSight Multimode Plate Reader

The EnSight multimode plate reader combines labeled & image-based cytometry technologies in a single benchtop platform. Imaging & online data analysis is fast: a 384-well plate can be imaged in less than 5 mins. The system’s modular design, combined with workflow-based Kaleido data acquisition & analysis software, gives a truly versatile plate reader that gets users productive quickly.

EnSpire Multimode Plate Reader

EnSpire® Multimode Plate Reader is designed to meet the demands of multi-user research environments, providing high performance technology and flexibility for a range of applications without compromising sensitivity. Combine this with our expertise and portfolio of reagents, PerkinElmer offers an unrivaled solution to your application needs.

EnSpire Plate Reader is available outside the EU. Please contact your local representative for further details.

VictorX_ImageA_320px

VICTOR Multilabel Plate Reader

The VICTOR Multilabel plate reader has been replaced by the VICTOR Nivo multimode plate reader. Please contact your local representative for further information, or visit the VICTOR Nivo product page (Part Number - HH35000500).
EnVision_Alone_Left_Angle

EnVision 2105 Multimode Plate Reader

The EnVision 2105 multimode plate reader provides exceptional speed, ultra-high throughput, and maximum sensitivity across all detection technologies. Tried and tested, the EnVision microplate reader gives you robust performance and reliable data for high throughput screening, time after time.

The EnVision 2105 model delivers even higher sensitivity for time-resolved fluorescence (TRF) applications, and the Enhanced Security software option includes tools to facilitate 21 CFR Part 11 compliance for integration into regulated environments (GxP). In addition, the Alpha 775 laser module is designed for plant assays.

EnSpire Alpha Plate Reader

The EnSpire Alpha Plate Reader provides proven Alpha technology to your lab at an affordable price and from the Alpha detection leader.

EnSpire Plate Reader is available outside the EU. Please contact your local representative for further details.

ViewLux uHTS Microplate Imager

The ViewLux® is the gold standard, ultra high-speed microplate imager, ideal for high throughput screening of compound libraries requiring the ultimate in speed, reliability and high quality data.

The ViewLux uHTS microplate imager is available outside the EU. Please contact your local representative to discuss alternative products.

LANCE Ultra ULight™-anti-GST

Goat polyclonal anti-GST tag antibody labeled with ULight™ dye.
Price Range : 414.00 EUR - 9800.00 EUR
AlphaPlex-545-antibody-bead2

Anti-Mouse IgG AlphaPlex-545 (Tb) Acceptor Beads

AlphaPlex-545 (Terbium) Acceptor beads conjugated to anti-mouse IgG antibody, for use in Alpha no-wash multiplexing assays.
Price Range : 610.00 EUR - 25000.00 EUR
AlphaPlex-545-antibody-bead2

Anti-human IgG AlphaPlex 545 Acceptor Beads

AlphaPlex™-545 (Terbium) Acceptor beads conjugated to anti-human IgG antibody, for use in Alpha no-wash multiplexing assays.
Price Range : 610.00 EUR - 25000.00 EUR
AlphaScreen Acceptor Beads

AlphaScreen Protein A Acceptor beads, 25 mg

AlphaScreen Acceptor beads conjugated to Protein A.
List Price : 8900.00 EUR

AlphaScreen DIG (Digoxin/Digoxigenin) Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-Dig (digoxin) conjugated AlphaScreen Acceptor beads. 
Price Range : 187.00 EUR - 14300.00 EUR

Anti-bovine IgA AlphaLISA Acceptor Beads

AlphaLISA Acceptor beads conjugated to anti-bovine IgA antibody. These beads can be used to capture bovine IgA antibodies.
Price Range : 827.00 EUR - 27900.00 EUR
PerkinElmer

Protein A AlphaPlex™ 545 Acceptor Beads

AlphaPlex™-545 (Terbium) Acceptor beads conjugated to Protein A, for use in Alpha no-wash multiplexing assays.
Price Range : 610.00 EUR - 25000.00 EUR
AlphaPlex-545-unconjugated

Unconjugated AlphaPlex-545 Acceptor Beads

Unconjugated AlphaPlex 545 (Terbium) Acceptor beads bear reactive aldehyde groups at their surface, allowing you to conjugate a wide variety of reagents using a simple reductive amination protocol.
Price Range : 1393.00 EUR - 29300.00 EUR
AlphaScreen Acceptor Beads

AlphaScreen Protein A Acceptor beads

AlphaScreen Acceptor beads conjugated to Protein A.
List Price : 1791.00 EUR

AlphaScreen GST Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-GST conjugated AlphaScreen Acceptor beads. This kit contains enough reagents to run 500 wells in 384-well format, using a 25 µL reaction volume.
Price Range : 187.00 EUR - 14300.00 EUR

AlphaScreen Histidine (Nickel Chelate) Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and nickel chelate (Ni-NTA) AlphaScreen Acceptor beads. This kit contains enough reagents to run 500 wells in 384-well format, using a 25 µL reaction volume.
Price Range : 187.00 EUR - 14300.00 EUR

LANCE Ultra ULight™-anti-6xHis

Mouse monoclonal anti-polyHistidine tag antibody labeled with ULight™ dye.
Price Range : 395.00 EUR - 9800.00 EUR
LANCE Detection Kit

EGF-EGFR LANCE Ultra TR-FRET Binding Kit

This kit is designed for the detection of binding activity between Human EGF and EGFR using a homogeneous LANCE Ultra TR-FRET assay. This assay can facilitate the design and development of therapeutics which competitively inhibit EGF/EGFR interaction.
Price Range : 802.00 EUR - 10700.00 EUR
AlphaPlex Samarium Acceptor Beads

Anti-Human IgG AlphaPlex 645 (Sm) Acceptor beads

AlphaPlex™-645 (Samarium) Acceptor beads conjugated to anti-human IgG antibody, for use in Alpha no-wash multiplexing assays.
Price Range : 610.00 EUR - 25000.00 EUR
Alpha_Donor_bead_1

AlphaScreen Streptavidin Donor beads

Alpha Donor beads conjugated to streptavidin.
Price Range : 374.00 EUR - 10500.00 EUR
AlphaPlex Samarium Acceptor Beads

Anti-6X His AlphaPlex 645 (Sm) Acceptor beads

AlphaPlex™-645 (Samarium) Acceptor beads conjugated to anti-6XHis antibody, for use in Alpha no-wash multiplexing assays.
Price Range : 610.00 EUR - 25000.00 EUR
PerkinElmer

SureLight Allophycocyanin-anti-GST antibody, 1 mg, lyophilized

APC-labeled anti-GST antibody, for capturing GST-tagged proteins and peptides in LANCE TR-FRET assays.
List Price : 437.00 EUR
Alpha binding assay principle

EGF/EGFR AlphaLISA Binding Kit

The AlphaLISA® EGF/EGFR Binding Kit is designed for the detection of binding activity between Human EGF and EGFR, using a homogeneous AlphaLISA assay (no wash steps). This assay can facilitate the design and development of therapeutics which competitively inhibit the EGF/EGFR interaction.
Price Range : 722.00 EUR - 10100.00 EUR
Alpha donor antibody coated

Anti-DIG Alpha Donor beads

Alpha Donor beads conjugated to anti-DIG (digoxin) antibody. This bead can be used to capture Dig-labeled biomolecules for Alpha no-wash assays.
Price Range : 533.00 EUR - 9100.00 EUR

Anti-human IgG (Fc specific) AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-human IgG antibody. These beads can be used to capture human IgG antibodies. The antibody conjugated to these beads is Fc-specific, and is a mouse polyclonal antibody.
Price Range : 610.00 EUR - 25000.00 EUR

Anti-c-myc AlphaLISA® Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-c-myc antibody. These beads can be used to capture c-myc-tagged proteins and peptides in AlphaLISA no-wash assays.
Price Range : 610.00 EUR - 25000.00 EUR

Anti-FITC AlphaLISA® Acceptor beads

AlphaLISA® Acceptor beads conjugated to mouse monoclonal anti-FITC antibody. These beads can be used to capture FITC-tagged and fluorescein-labeled biomolecules for AlphaLISA no-wash assays.
Price Range : 610.00 EUR - 25000.00 EUR

AlphaScreen General IgG (Protein A) Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Protein A conjugated AlphaScreen Acceptor beads.
Price Range : 93.00 EUR - 14300.00 EUR

AlphaLISA anti-mouse IgG Acceptor beads

AlphaLISA Acceptor beads conjugated to anti-mouse IgG antibody. This antibody is not Fc-specific; for Fc-specific beads, please see product AL105.
Price Range : 586.00 EUR - 24100.00 EUR

Protein G AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to Protein G. These beads can be used to capture antibodies that associate with Protein G.
Price Range : 610.00 EUR - 25000.00 EUR

Nickel Chelate AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to nickel chelate. These beads can be used to capture His-tagged proteins and peptides.
Price Range : 610.00 EUR - 25000.00 EUR

MMP-7 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human MMP7 enables the detection and quantitation of human pro- and active MMP-7 (hMMP-7) in serum, buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 462.00 EUR - 10100.00 EUR

AlphaScreen Mouse IgG Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-mouse IgG conjugated AlphaScreen Acceptor beads.
Price Range : 187.00 EUR - 14300.00 EUR

Anti-C-tag AlphaLISA Acceptor Beads

AlphaLISA Acceptor beads conjugated to anti-C-tag antibody. These beads can be used to capture C-tag proteins, and can be used in conjunction with Alpha Donor beads to create AlphaLISA no-wash assays.
Price Range : 610.00 EUR - 25000.00 EUR

Anti-Maltose-Binding Protein (MBP) AlphaLISA® Acceptor beads

AlphaLISA® Acceptor beads conjugated to anti-MBP (maltose-binding protein) antibody. The antibody is a rat monoclonal antibody, clone MBP 7G4. These beads can be used to capture MBP-tagged proteins for AlphaLISA no-wash assays.
Price Range : 610.00 EUR - 25000.00 EUR
Alphaplex-545-terbium-glutathione

Glutathione AlphaPlex™ 545 Acceptor Beads

AlphaPlex™-545 (Terbium) Acceptor beads conjugated to glutathione, for use in Alpha no-wash multiplexing assays.
Price Range : 610.00 EUR - 25000.00 EUR
AlphaPlex-545-antibody-bead2

Anti-HA AlphaPlex 545 (Tb) Acceptor Beads

AlphaPlex™-545 (Terbium) Acceptor beads conjugated to anti-HA (hemaglutinin) antibody. These beads can be used to capture HA-tagged proteins and peptides.
Price Range : 610.00 EUR - 25100.00 EUR

Anti-FLAG AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-FLAG antibody. This mouse monoclonal M2 clone recognizes the FLAG sequence at the N-terminus, Met N-terminus, C-terminus, and internal sites.
Price Range : 610.00 EUR - 25000.00 EUR
DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

DELFIA Tb-N1 Streptavidin

Terbium-labeled streptavidin for binding biotinylated biomolecules in DELFIA® time-resolved fluorescence (TRF) assays.
Price Range : 270.00 EUR - 1840.00 EUR

Glutathione AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to glutathione. These beads can be used to capture GST-tagged proteins and peptides.
Price Range : 610.00 EUR - 25000.00 EUR

Anti-GFP AlphaLISA® Acceptor beads

AlphaLISA® Acceptor beads conjugated to anti-GFP antibody. The antibody is a mouse monoclonal antibody that recognizes wildtype and recombinant GFP (rGFP), and cross-reacts with eGFP. These beads can be used to capture GFP-tagged proteins for AlphaLISA no-wash assays.
Price Range : 610.00 EUR - 25000.00 EUR
DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

DELFIA® Eu-N1 Anti-6xHis

Europium-labeled anti-6X His antibody, for capturing His-tagged proteins in DELFIA® TRF assays. The anti-6xHis antibody is a purified mouse IgG1 monoclonal antibody. It is raised against a polypeptide containing a 6x histidine tag. The antibody has been shown to detect polyhistidine tags localized at the amino- or carboxyl-terminus.
Price Range : 409.00 EUR - 3816.00 EUR

LANCE® Eu-W1024 labeled anti-GST antibody

Europium-labeled anti-GST antibody, for capturing GST-tagged proteins in LANCE® TR-FRET assays.
Price Range : 186.00 EUR - 9200.00 EUR
PerkinElmer

LANCE Eu-anti-C-tag antibody

Europium-labeled anti-C-tag antibodies for LANCE® TR-FRET assays. This mouse monoclonal IgG1 antibody recognizes N-terminal and C-terminal Protein C tagged fusion proteins. The anti-C-tag antibody can be used to capture C-tag proteins, and can be used in conjunction with LANCE ULight or SureLight™ APC-labeled reagents to create LANCE TR-FRET assays.
Price Range : 330.00 EUR - 9300.00 EUR
PerkinElmer

LANCE Eu-W1024 Anti-c-Myc

Europium-labeled anti-c-myc antibody, for capturing c-myc-tagged proteins in LANCE® TR-FRET assays.
Price Range : 262.00 EUR - 12600.00 EUR
PerkinElmer

LANCE Eu-W1024 anti-FITC

Eu-W1024 labeled anti-FITC antibodies for LANCE® TR-FRET assays. The anti-FITC antibody is a purified mouse IgG2a monoclonal antibody.
Price Range : 330.00 EUR - 9200.00 EUR

AlphaScreen FLAG (M2) Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-FLAG conjugated AlphaScreen Acceptor beads. 
Price Range : 187.00 EUR - 14300.00 EUR

Anti-mouse IgG (Fc specific) AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-mouse IgG antibody. These beads can be used to capture mouse IgG antibodies. The antibody is Fc-specific, and is a goat polyclonal F(ab')2 fragment.
Price Range : 610.00 EUR - 25000.00 EUR

AlphaScreen FITC (Fluorescein) Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-FITC conjugated AlphaScreen Acceptor beads. 
Price Range : 199.00 EUR - 14300.00 EUR

"Protein-protein Interaction Research" 1-50 of 119 Products and Services

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