PerkinElmer

Protein-protein Interaction

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Accurately measure the function of proteins and gain new insights into protein-protein interaction (PPI) to modulate cellular processes. Inhibition and stabilization of these interactions using small molecules provides a mechanism that can be targeted for drug discovery.

We offer the technology to measure protein-protein interaction such as:

  • Transient and stable interactions
  • Low-to-high affinity interactions (pM to mM affinity)
  • Full-length protein-protein binding
  • Peptide-protein
  • Receptor dimerization
  • Protein-small molecule
  • Protein complex interactions

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  • Resources, Events & More

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Product Type
  • Accessories (4)
  • Instruments (6)
  • Reagents (103)
Antibody Conjugates
  • Anti-6X His (7)
  • Anti-bovine IgA (1)
  • Anti-c-Myc (4)
  • Anti-C-tag (3)
  • Anti-DIG (2)
  • Anti-DNP (2)
  • Anti-FITC (3)
  • Anti-FLAG (6)
  • Anti-GFP (2)
  • Anti-goat IgG (1)
  • Anti-GST (5)
  • Anti-HA (4)
  • Anti-HRP (2)
  • Anti-human IgG (3)
  • Anti-MBP (1)
  • Anti-mouse IgG (3)
  • Anti-rabbit IgG (2)
  • Anti-rat IgG (2)
  • Anti-V5 (3)
  • Glutathione (3)
  • Nickel chelate (1)
  • Protein A (5)
  • Protein G (1)
  • Protein L (1)
  • Strep-Tactin (1)
  • Streptavidin (11)
  • Streptavidin/Anti-c-Myc (1)
  • Streptavidin/Anti-DIG (1)
  • Streptavidin/Anti-FITC (1)
  • Streptavidin/Anti-FLAG (1)
  • Streptavidin/Anti-GST (1)
  • Streptavidin/Anti-HA (1)
  • Streptavidin/Anti-mouse IgG (1)
  • Streptavidin/Anti-rabbit IgG (1)
  • Streptavidin/Nickel chelate (1)
  • Streptavidin/Protein A (1)
  • Unconjugated (2)
Application
  • Antibody binding (1)
  • Enzymatic (5)
  • Isotyping (1)
  • Multiplexing (2)
  • Protein Analysis & Detection (44)
  • Protein-nucleic acid interactions (4)
  • Protein-protein interactions (88)
Assay points(200-50,000)
  • 100 (5)
  • 10000 (11)
  • 500 (18)
  • 5000 (5)
  • 50000 (10)
Assay Target
  • COX-2 (2)
  • EGF (2)
  • EGFR (3)
  • FCGR3A (2)
  • Histone H4 (2)
  • MMP-7 (1)
  • PD-1 (1)
  • PD-L1 (2)
Assay Target Class
  • Fc-receptor (2)
  • Histone (2)
  • Protein (8)
Automation Compatible
  • Yes (106)
Detection Method
  • Absorbance (5)
  • Alpha (61)
  • DELFIA TRF (7)
  • Fluorescence (5)
  • Fluorescence Polarization (3)
  • Image-based Cytometry (1)
  • Label-free (2)
  • Luminescence (5)
  • Time-Resolved Fluorescence (TRF) (31)
  • TR-FRET (19)
Experimental Type
  • In vitro (79)
Fluorophore
  • Eu-N1 (5)
  • Eu-W1024 (9)
  • Eu-W8044 (1)
  • Sm-N1 (1)
  • SureLight APC (4)
  • Tb-N1 (1)
  • ULight (8)
Format
  • Microplates (85)
Maximum Temperature (Celsius)
  • 40-50 (2)
  • 50-60 (2)
Molecular Modification
  • Acetylation (2)
Product Brand Name
  • Alpha (6)
  • AlphaLISA (36)
  • AlphaPlex (16)
  • AlphaScreen (12)
  • DELFIA (7)
  • EnSight (1)
  • EnSpire (3)
  • EnVision (3)
  • LANCE (10)
  • LANCE SureLight (4)
  • LANCE Ultra (11)
  • Victor (1)
  • ViewLux (1)
Target Species
  • Human (10)
Therapeutic Area
  • Biologics/Bioprocess (2)
  • Cancer (8)
  • Epigenetics (2)

"Protein-protein Interaction" 1-50 of 113 Products and Services

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VictorX_ImageA_320px

VICTOR Multilabel Plate Reader

The next generation VICTOR X Multilabel Plate Reader platform delivers flexibility, speed and performance to research labs of all sizes.
EnVision_Alone_Left_Angle

EnVision Multilabel Plate Reader

The EnVision Multilabel Plate Reader provides exceptional speed, ultra-high throughput, and maximum sensitivity across all detection technologies. Tried and tested, the EnVision microplate reader gives you robust performance and reliable data for high throughput screening, time after time.

EnSpire Alpha Plate Reader

The EnSpire Alpha Plate Reader provides proven Alpha technology to your lab at an affordable price and from the Alpha detection leader.

EnSpire Plate Reader is available outside the EU. Please contact your local representative for further details.

EnSight multimode plate-reader

EnSight Multimode Plate Reader

The EnSight multimode plate reader combines labeled, label-free* & image-based cytometry technologies in a single benchtop platform. Imaging & online data analysis is fast: a 384-well plate can be imaged in less than 5 mins. The system’s modular design, combined with workflow-based Kaleido data acquisition & analysis software, gives a truly versatile plate reader that gets users productive quickly.

*Label free detection module of EnSight Plate Reader is available outside the EU. Please contact your local representative for further details.

EnSpire Multimode Plate Reader

EnSpire® Multimode Plate Reader is designed to meet the demands of multi-user research environments, providing high performance technology and flexibility for a range of applications without compromising sensitivity. Combine this with our expertise and portfolio of reagents, PerkinElmer offers an unrivaled solution to your application needs.

EnSpire Plate Reader is available outside the EU. Please contact your local representative for further details.

ViewLux uHTS Microplate Imager

The ViewLux® is the gold standard, ultra high-speed microplate imager, ideal for high throughput screening of compound libraries requiring the ultimate in speed, reliability and high quality data.

The ViewLux uHTS microplate imager is available outside the EU. Please contact your local representative to discuss alternative products.

AlphaScreen HA (Hemagglutinin) Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-HA (hemagglutinin) conjugated AlphaScreen Acceptor beads. 
Price Range : 181.00 EUR - 13900.00 EUR
AlphaPlex Samarium Acceptor Beads

Unconjugated AlphaPlex™ 545 Acceptor Beads

Unconjugated AlphaPlex 645 (Samarium) Acceptor beads bear reactive aldehyde groups at their surface, allowing you to conjugate a wide variety of reagents using a simple reductive amination protocol.
Price Range : 1353.00 EUR - 28500.00 EUR
AlphaScreen Acceptor Beads

AlphaScreen Protein A Acceptor beads, 25 mg

AlphaScreen Acceptor beads conjugated to Protein A.
List Price : 8600.00 EUR
PerkinElmer

LANCE Eu-W1024 Streptavidin

Europium-labeled streptavidin, for capturing biotinylated biomolecules in LANCE TR-FRET assays.
Price Range : 891.00 EUR - 7800.00 EUR

Anti-goat IgG (Fc specific) AlphaLISA® Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-goat IgG antibody. These beads can be used to capture goat IgG antibodies. The antibody is Fc-specific, and is a rabbit polyclonal F(ab')2 fragment.
Price Range : 592.00 EUR - 24300.00 EUR

Anti-HA AlphaLISA Acceptor Beads

AlphaLISA Acceptor beads conjugated to anti-HA (hemagglutinin) antibody. These beads can be used to capture HA-tagged proteins and peptides.
Price Range : 592.00 EUR - 24300.00 EUR

AlphaScreen General IgG (Protein A) Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Protein A conjugated AlphaScreen Acceptor beads.
Price Range : 91.00 EUR - 13900.00 EUR
DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

DELFIA® Eu-N1 Anti-c-myc

Europium-labeled anti-c-myc antibody, for capturing c-myc-tagged proteins in DELFIA® TRF assays.
Price Range : 537.00 EUR - 5100.00 EUR

LANCE Ultra ULight™-Streptavidin

Streptavidin labeled with ULight™ dye.
Price Range : 270.00 EUR - 5300.00 EUR

AlphaScreen GST Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-GST conjugated AlphaScreen Acceptor beads. This kit contains enough reagents to run 500 wells in 384-well format, using a 25 µL reaction volume.
Price Range : 181.00 EUR - 13900.00 EUR

ULight anti-FITC

ULight™ labeled anti-FITC antibody for LANCE® TR-FRET assays. The anti-FITC antibody is a purified mouse IgG2a monoclonal antibody.
Price Range : 431.00 EUR - 10900.00 EUR

Anti-FITC AlphaLISA® Acceptor beads

AlphaLISA® Acceptor beads conjugated to mouse monoclonal anti-FITC antibody. These beads can be used to capture FITC-tagged and fluorescein-labeled biomolecules for AlphaLISA no-wash assays.
Price Range : 592.00 EUR - 24300.00 EUR
DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

DELFIA Sm-N1 Streptavidin

Samarium-labeled streptavidin for binding biotinylated biomolecules in DELFIA® time-resolved fluorescence (TRF) assays.
Price Range : 262.00 EUR - 1786.00 EUR

Protein L AlphaLISA® Acceptor beads

AlphaLISA® Acceptor beads conjugated to Protein L. These beads can be used to capture antibodies that bind Protein L for AlphaLISA no-wash assays.
Price Range : 592.00 EUR - 24300.00 EUR

Anti-GST AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-GST antibody. These beads can be used to capture GST-tagged proteins and peptides in AlphaLISA no-wash assays.
Price Range : 592.00 EUR - 24300.00 EUR

ULight anti-c-myc antibody

ULight labeled anti-c-myc antibody for LANCE® TR-FRET assays.
Price Range : 431.00 EUR - 10900.00 EUR
DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

DELFIA® Eu-N1 Anti-GST

Europium-labeled anti-GST antibody, for capturing GST-tagged proteins in DELFIA® TRF assays.
Price Range : 226.00 EUR - 2774.00 EUR

Anti-HRP AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-HRP antibody. These beads can be used to capture HRP-fusion proteins for AlphaLISA no-wash assays.
Price Range : 575.00 EUR - 23600.00 EUR
PerkinElmer

AlphaLISA BRD4_BD2 / H4 K5,8,12,16Ac Binding Kit

This kit is designed for the detection of binding activity between bromodomain-containing protein 4, Bromodomain2: BRD4 (BD2) and acetylated histone H4 peptide (H4 K5,8,12,16Ac) using a homogeneous AlphaLISA assay (no wash steps). The assay allows screening of BRD4 inhibitors with a highly-specific substrate.
List Price : 700.00 EUR
AlphaPlex-545-unconjugated

Unconjugated AlphaPlex-545 Acceptor Beads

Unconjugated AlphaPlex 545 (Terbium) Acceptor beads bear reactive aldehyde groups at their surface, allowing you to conjugate a wide variety of reagents using a simple reductive amination protocol.
Price Range : 1353.00 EUR - 28500.00 EUR
PerkinElmer

SureLight Allophycocyanin-streptavidin (APC-SA), protein binding assay, Iyophilized

APC-labeled streptavidin, for use in LANCE® TR-FRET protein binding assays.
Price Range : 339.00 EUR - 9500.00 EUR
Alpha donor antibody coated

Anti-DIG Alpha Donor beads

Alpha Donor beads conjugated to anti-DIG (digoxin) antibody. This bead can be used to capture Dig-labeled biomolecules for Alpha no-wash assays.
Price Range : 485.00 EUR - 8800.00 EUR

Protein A AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to Protein A. These beads can be used to capture antibodies that associate with Protein A.
Price Range : 592.00 EUR - 24300.00 EUR
Alpha donor antibody coated

Anti-HRP Alpha Donor Beads

Alpha Donor beads conjugated to anti-HRP antibody. These beads can be used to capture HRP-fusion proteins for Alpha no-wash detection, binding, and other assays.
Price Range : 471.00 EUR - 8500.00 EUR

EGF-EGFR LANCE Ultra TR-FRET Binding Kit

This kit is designed for the detection of binding activity between Human EGF and EGFR using a homogeneous LANCE Ultra TR-FRET assay. This assay can facilitate the design and development of therapeutics which competitively inhibit EGF/EGFR interaction.
Price Range : 779.00 EUR - 10400.00 EUR

Anti-Maltose-Binding Protein (MBP) AlphaLISA® Acceptor beads

AlphaLISA® Acceptor beads conjugated to anti-MBP (maltose-binding protein) antibody. The antibody is a rat monoclonal antibody, clone MBP 7G4. These beads can be used to capture MBP-tagged proteins for AlphaLISA no-wash assays.
Price Range : 592.00 EUR - 24300.00 EUR

Strep-Tactin® AlphaLISA® Acceptor beads

AlphaLISA® Acceptor beads conjugated to Strep-Tactin®. These beads can be used to capture Strep-tag® II-tagged proteins for AlphaLISA no-wash assays.
Price Range : 576.00 EUR - 23600.00 EUR
AlphaLisa Analyte 2

EGFR (human), lyophilized (AlphaLISA)

EGFR (human), for use in the AlphaLISA EGF/EGFR Binding Assay.
List Price : 242.00 EUR

Protein G AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to Protein G. These beads can be used to capture antibodies that associate with Protein G.
Price Range : 592.00 EUR - 24300.00 EUR

LANCE® Eu-W1024 labeled anti-GST antibody

Europium-labeled anti-GST antibody, for capturing GST-tagged proteins in LANCE® TR-FRET assays.
Price Range : 180.00 EUR - 8900.00 EUR

Anti-DIG AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to a mouse monoclonal anti-Dig (digoxin) antibody. These beads can be used to capture Dig-labeled proteins, peptides, and other biomolecules to create AlphaLISA no-wash assays.
Price Range : 592.00 EUR - 24300.00 EUR

Anti-FLAG AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-FLAG antibody. This mouse monoclonal M2 clone recognizes the FLAG sequence at the N-terminus, Met N-terminus, C-terminus, and internal sites.
Price Range : 592.00 EUR - 24300.00 EUR
DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

DELFIA® Eu-N1 Anti-HA

Europium-labeled anti-HA antibody for binding HA-tagged proteins in DELFIA® time-resolved fluorescence (TRF) assays. The anti-HA antibody is a purified IgG2b subclass of mouse monoclonal antibody. It recognizes the epitope sequence (YPYDVPDYA) derived from the human influenza hemagglutinin (HA) protein.
Price Range : 537.00 EUR - 5100.00 EUR
AlphaScreen Acceptor Beads

AlphaScreen Protein A Acceptor beads

AlphaScreen Acceptor beads conjugated to Protein A.
List Price : 1739.00 EUR

Anti-mouse IgG (Fc specific) AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-mouse IgG antibody. These beads can be used to capture mouse IgG antibodies. The antibody is Fc-specific, and is a goat polyclonal F(ab')2 fragment.
Price Range : 592.00 EUR - 24300.00 EUR

AlphaScreen FITC (Fluorescein) Detection Kit

AlphaScreen® no-wash assay kit containing Streptavidin Donor beads and Anti-FITC conjugated AlphaScreen Acceptor beads. 
Price Range : 181.00 EUR - 13900.00 EUR
AlphaLISA immunoassay kits

COX-2 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human COX-2 enables the detection and quantitation of human COX-2 in cell culture supernatants and cell extracts using a homogeneous AlphaLISA assay (no wash steps). The assay shows no cross-reactivity with human COX-1 nor with sheep COX-2.
Price Range : 4256.00 EUR - 31500.00 EUR
PerkinElmer

AlphaLISA BRD4_BD1 / H4 K5,8,12,16Ac Binding Kit

This kit is designed for the detection of binding activity between bromodomain-containing protein 4, Bromodomain1: BRD4 (BD1) and acetylated histone H4 peptide (H4 K5,8,12,16Ac) using a homogeneous AlphaLISA assay (no wash steps). The assay allows screening of BRD4 inhibitors with a highly-specific substrate.
List Price : 700.00 EUR

Streptavidin AlphaLISA® Acceptor beads

AlphaLISA® Acceptor beads conjugated to streptavidin. These beads can be used to capture biotinylated proteins, peptides, nucleic acids (DNA and RNA), and small molecules for AlphaLISA no-wash assays.
Price Range : 592.00 EUR - 24300.00 EUR

Anti-C-tag AlphaLISA Acceptor Beads

AlphaLISA Acceptor beads conjugated to anti-C-tag antibody. These beads can be used to capture C-tag proteins, and can be used in conjunction with Alpha Donor beads to create AlphaLISA no-wash assays.
Price Range : 593.00 EUR - 24300.00 EUR
DELFIA; Eu-N1 Rabbit Anti-Mouse-IgG

DELFIA Tb-N1 Streptavidin

Terbium-labeled streptavidin for binding biotinylated biomolecules in DELFIA® time-resolved fluorescence (TRF) assays.
Price Range : 262.00 EUR - 1786.00 EUR

Anti-rat IgG (Fc specific) AlphaLISA® Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-rat IgG antibody. These beads can be used to capture rat IgG antibodies. The antibody is Fc-specific, and is a goat polyclonal F(ab')2 fragment.
Price Range : 592.00 EUR - 24300.00 EUR
AlphaPlex Samarium Acceptor Beads

Anti-FLAG AlphaPlex-645 Acceptor Beads

AlphaPlex-645 (Samarium) Acceptor beads conjugated to anti-FLAG antibody, for use in Alpha no-wash multiplexing assays.
Price Range : 592.00 EUR - 24300.00 EUR

Anti-rabbit IgG (Fc specific) AlphaLISA Acceptor Beads

AlphaLISA® Acceptor beads conjugated to anti-rabbit IgG antibody. These beads can be used to capture rabbit IgG antibodies. The antibody is Fc-specific, and is a goat polyclonal F(ab')2 fragment.
Price Range : 592.00 EUR - 24300.00 EUR

"Protein-protein Interaction" 1-50 of 113 Products and Services

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