PerkinElmer

Ligands

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Eliminate the need for antibodies and reduce assay time with direct detection using our radiolabeled ligands, which provide for sensitive and quantitative measurement of binding.

  • High specific activity — The majority of our 125I-labeled ligands are offered at maximum specific activity. This means virtually every molecule of ligand provided in the stock vial is radiolabeled. For tritiated ligands (3H ligands), pick a ligand with specific activity above 20 Ci/mmol – all of our tritiated ligands meets or exceeds these requirements.
  • High purity — We offer highly-pure radioligands for the highest specific signal with low background in binding assays.
  • High selectivity — Our broad portfolio of agonists and antagonists offers many options for choosing the most selective compound for your receptor.
  • Validated for receptor binding — all of our radioligand products are tested for receptor binding during development. Additionally, many of our radioligands are used to QC our GPCR and receptor cell lines and cell membrane products.

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  • 1.0 - 10 µCi/mL (3)
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Radionuclide
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Radioisotope
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"Ligands" 1-50 of 125 Products and Services

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Neurotensin, [3,11-Tyrosyl-3,5-3H(N)]

Neurotensin radioligand tritiated at the 3,5 position of the tyrosine residues. Neurotensin is a neuropeptide that acts as an agonist on the neurotensin receptor family.
Price Range : 935.00 EUR - 4911.00 EUR

Ro 15-1788, [N-Methyl-3H]

Ro 15-1788 (flumazenil), tritiated on the N-methyl group. Ro 15-1788 acts as a selective benzodiazepine antagonist.
Price Range : 913.00 EUR - 6800.00 EUR

Histamine Dihydrochloride, [Ring, Methylenes-3H(N)]

Histamine dihydrochloride, tritiated on the ring and methylene groups. Histamine is an endogenous agonist of histamine receptors.
Price Range : 1519.00 EUR - 3305.00 EUR

Norepinephrine, Levo-[ring-2,5,6-3H]

Levo-Norepinephrine, tritiated on the ring group. Norepinephrine binds and activates adrenergic receptors, and is cleared by the norepinehprine transporter (NET).
Price Range : 1865.00 EUR - 11900.00 EUR

Dihydroalprenolol Hydrochloride, Levo-[Ring, Propyl-3H(N)]

Dihydroalprenolol hydrochloride, tritiated on the ring propyl group. Dihydroalprenolol (DHA) is an alprenolol derivative that binds to beta-adrenergic receptors and acts as a beta-adrenergic blocker.
Price Range : 1378.00 EUR - 3133.00 EUR

5-Hydroxytryptamine Creatinine Sulfate, [1,2-3H(N)]

5-Hydroxytryptamine Creatinine Sulfate (Serotonin, 5-HT), tritiated at the 1,2 position. 5-Hydroxytryptamine is a neurotransmitter and is the endogenous ligand for serotonin receptors.
Price Range : 1049.00 EUR - 2835.00 EUR

Chloramphenicol, [Ring-3,5-3H]

Chloramphenicol, tritiated at the ring-3,5 position. Chloramphenicol is a broad spectrum antibiotic that binds to a receptor site on the 50S subunit of the bacterial ribosome, inhibiting peptidyl transferase.
Price Range : 2652.00 EUR - 5800.00 EUR

17α-HYDROXYPROGESTERONE, [1,2,6,7-3H]

17α-Hydroxyprogesterone (17α-OHP), tritiated at the 1,2,6,7 position. 17α-Hydroxyprogesterone is an agonist of the progesterone receptor (PR), an antagonist of the mineralocorticoid receptor (MR), and a partial agonist of the glucocorticoid receptor.
List Price : 2078.00 EUR

Prazosin, [7-Methoxy-3H]

Prazosin, tritiated at the 7-methoxy position. Prazosin acts as an inverse agonist at the α1-adrenergic receptor.
Price Range : 982.00 EUR - 7800.00 EUR

Pirenzepine, [N-Methyl-3H]

Pirenzepine, tritiated on the N-methyl group. Pirenzepine acts as a selective antagonist of the muscarinic M1 acetylcholine receptor.
Price Range : 2730.00 EUR - 6900.00 EUR

GABAPENTIN [3H]

Tritiated gabapentin (Neurontin). Gabapentin is a medication used to treat epilepsy, and has been shown to cross membrane lipid barriers via system L-amino acid transporters and bind to voltage-gated calcium channels in the central nervous system.
List Price : 7500.00 EUR

Clonidine Hydrochloride, [Benzene Ring-3H]-, 250µCi (9.25MBq)

Clonidine hydrochloride, tritiated on the benzene ring. Clonidine is a drug used to treat high blood pressure, ADHD, anxiety disorders, and drug withdrawal and acts as an agonist at α2 adrenergic and imidazoline receptors.
List Price : 1838.00 EUR

5-CT, [3H]

5-carboxyamidotryptamine (5-CT) labeled with tritium. 5-CT is a tryptamine derivative closely related to the neurotransmitter serotonin. 5-CT acts as a non-selective, high-affinity full agonist at the 5-HT1A, 5-HT1B, 5-HT1D, 5-HT5A, and 5-HT7 serotonin receptors. It also binds the 5-HT2, 5-HT3, 5-HT6 serotonin receptors with lower affinity.
List Price : 1775.00 EUR

Enkephalin, [Tyrosyl-2,6-3H(N)]- (2-D-Penicillamine, 5-D-Penicillamine) (DPDPE)

2-D-Penicillamine, 5-D-Penicillamine (DPDPE), tritiated on the tyrosyl group. Cyclic peptide, sequence: Tyr-D-Pen-Gly-Phe-D-Pen-OH. DPDPE is a synthetic enkephalin opioid peptide that acts as an agonist at delta opiate receptors (δ-opioid receptor, DOR).
Price Range : 1366.00 EUR - 6600.00 EUR

Dihydroxyphenylethylamine, 3,4-[7-3H]

Dihydroxyphenylethylamine (dopamine, DA), tritiated at the 7 position. Dihydroxyphenylethylamine is a neurotransmitter and is the primary endogenous ligand for dopamine receptors.
Price Range : 1127.00 EUR - 3162.00 EUR

WIN 35428, [N-Methyl-3H]

WIN 35428 [(–)-2-β-Carbomethoxy-3-β-(4-fluorophenyl)tropane], tritiated on the N-methyl group. WIN 35428 acts as an antagonist at dopamine transporters (DATs).
Price Range : 992.00 EUR - 7100.00 EUR

(+)-Pentazocine, [Ring-1,3-3H]

(+)-Pentazocine radioligand tritiated at the 1,3 position on the ring. Pentazocine is a synthetic opioid shown to bind sigma 1 receptor.
Price Range : 874.00 EUR - 6800.00 EUR

Hydroxytryptamine Binoxalate (Serotonin Binoxalate), 5-[1-14C]

5-Hydroxytryptamine Binoxalate (Serotonin Binoxalate), labeled with C-14 at the 1-position. 5-Hydroxytryptamine is a neurotransmitter and is the endogenous ligand for serotonin receptors. NEC855 replaces product NEC225, which was labeled at the 2-position.
Price Range : 1073.00 EUR - 4596.00 EUR

GR 65630, [N-Methyl-3H]

GR 65630, tritiated on the N-methyl group. GR 65630 acts as a selective antagonist at the 5-HT3 receptor.
Price Range : 903.00 EUR - 4389.00 EUR

Nicotine, L-(-)-[N-Methyl-3H]

Nicotine radioligand tritiated on the methyl residue. Nicotine acts as an agonist at most nicotinic acetylcholine receptors; however it acts as an antagonist at two nicotinic receptor subunits (nAChRα9 and (nAChRα10). 
Price Range : 702.00 EUR - 5400.00 EUR

TCP, [Piperdyl-3,4-3H(N)]

Tenocyclidine (TCP), tritiated at the piperdyl-3,4 position. TCP acts as an antagonist at N-methyl-D-aspartate receptor (NMDA receptors).
Price Range : 911.00 EUR - 3321.00 EUR

Kainic acid, [Isopropenyl-3H]

Kainic acid, tritiated on the isoproprenyl group. Kainic acid acts as an agonist at kainate glutamate receptors.
Price Range : 799.00 EUR - 7400.00 EUR

Substance-P (9-Sar, 11-Met(O2)), [2-Prolyl-3,4-3H]-, 50µCi (1.85MBq)

Substance-P, tritiated on the 2-prolyl group. Substance-P acts as an antagonist at neurokinin-1 receptors (NK1Rs).
List Price : 3532.00 EUR

U-69,593, [Phenyl-3,4-3H]

U-69,593, tritiated at the phenyl-3,4 position. U-69,593 is a selective κ1-opioid receptor agonist.
Price Range : 973.00 EUR - 3170.00 EUR

Caffeine, [1-Methyl-14C]-, 50µCi (1.85MBq)

Caffeine, radiolabeled with C-14 at the 1-methyl position. Caffeine acts as a non-selective antagonist at adenosine receptors.
List Price : 1148.00 EUR

Scopolamine Methyl Chloride, [N-methyl-3H]

Scopolamine methyl chloride, tritiated on the N-methyl group. Scopolamine acts as an antagonist at muscarinic acetylcholine receptors.
Price Range : 2128.00 EUR - 4880.00 EUR

RO 15-4513, [7,9-3H]-, 250µCi (9.25MBq)

Ro15-4513, tritiated at the 7,9 position. Ro15-4513 is a partial inverse agonist at GABAA receptors.
List Price : 3384.00 EUR

Lysergic Acid Diethylamide, [N-Methyl-3H]-, 250µCi (9.25MBq)

Lysergic Acid Diethylamide (LSD), tritiated on the N-methyl group. LSD is a partial agonist of dopamine D2 receptors. It also binds most serotonin receptors (5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT5A, 5-HT5B and 5-HT6).
List Price : 2772.00 EUR

Vinblastine Sulphate, [G-3H]

Vinblastine sulphate, tritiated. Vinblastine binds to tubulin and inhibits microtubule formation.
Price Range : 2153.00 EUR - 8000.00 EUR

BRL-43694, [9-Methyl-3H]

Please note that as of Jan 1, 2016, this product will be discontinued.
List Price : 3947.00 EUR

Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid (AMPA), DL-α-[5-Methyl-3H]

DL-α-Amino-3-Hydroxy-5-Methylisoxazole-4-Propionic Acid (AMPA), tritiated at the 5-methyl position. AMPA acts as an agonist at the AMPA receptor.
Price Range : 797.00 EUR - 5900.00 EUR

Batrachotoxinin A 20-α-Benzoate, [Benzoyl-2,5-3H]

Batrachotoxinin A 20-alpha-benzolate (BTX-B) tritiated at the benzoyl-2,5 position. Batrachotoxinin-A 20-alpha-benzoate is an analog of batrachotoxin (BTX), and is a ligand for voltage-sensitive sodium channels. BTX-B will now be made available on a fresh lot schedule to be determined for 2018.

Spiperone (Spiroperidol), [Benzene ring-3H]

Spiperone, tritiated on the benzene ring. Spiperone acts as an antagonist at Dopamine D2 and D3 receptors, 5-HT1A, 5-HT2A, and alpha-adrenergic receptors (α adrenoreceptors).
List Price : 4974.00 EUR

Flunitrazepam, [Methyl-3H]

Flunitrazepam (Rohypnol), tritiated on the methyl group. Flunitrazepam is a benzodiazepine and acts as an agonist at GABAA (γ-aminobutyric acid) receptors.
Price Range : 744.00 EUR - 7500.00 EUR

MK-912, [3H(G)]

MK-912 radioligand. MK-912 acts as a selective antagonist at the α2-adrenoceptor.
Price Range : 559.00 EUR - 4060.00 EUR

DICLOFENAC SODIUM[PHENYLACETIC ACID RING- U-14C]

Diclofenac sodium, labeled with C-14 on the phenylacetic acid ring. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that acts as an antagonist at peroxisome prolifeator-activated receptor gamma (PPAR-γ or PPARG).
List Price : 3297.00 EUR

DOFETILIDE, [N-METHYL-3H], 100 µCi

Dofetilide, tritiated at the N-methyl position. Dofetilide is a selective potassium channel (hERG) blocker.
List Price : 2216.00 EUR

Pyrilamine (Mepyramine), [pyridinyl 5-3H]-, 250µCi (9.25MBq)

Pyrilamine (Mepyramine), tritiated at the pyridinyl 5 position. Pyrilamine acts as an antagonist at the histamine H1 receptor.
List Price : 2212.00 EUR

Acetylcholine Iodide, [acetyl-3H], 1mCi (37MBq)

Acetylcholine (Ach) radioligand tritiated on the acetyl group. Acetylcholine is a neurotransmitter and the endogeous ligand that binds to and activates muscarinic and nicotinic acetylcholine receptors.
List Price : 869.00 EUR

Ketanserin Hydrochloride (R41 468), [Ethylene-3H]

Ketanserin hydrochloride (Sufrexal; R41468), tritiated on the ethylene group. Ketanserin is a high-affinity non-selective antagonist of 5-HT2 receptors.
Price Range : 865.00 EUR - 7700.00 EUR

AF-DX 384, [2,3-Dipropylamino-3H]-, 250µCi (9.25MBq)

AFDX-384 (BIBN-161) radioligand tritiated at the 2,3-dipropylamino position. AFDX-384 acts as a selective antagonist of muscarinic acetylcholine receptors, with selectivity for the M2 and M4 subtypes.
List Price : 2738.00 EUR

MK-801, (+)-[3-3H]-

(+)-MK-801 radioligand tritriated at the 3 position. MK-801 acts as a non-competitive antagonist at the glutamate receptor, N-Methyl-D-aspartate (NMDA).
Price Range : 913.00 EUR - 6400.00 EUR

Oxotremorine-M Acetate, [Methyl-3H]-,>97%, 250µCi (9.25MBq)

Oxotremorine-M acetate, tritiated on the methyl group. Oxotremorine-M acts as a selective agonist at muscarinic acetylcholine receptors.
List Price : 3220.00 EUR

Dihydroxyphenylethylamine (Dopamine), 3,4-[Ring-2,5,6-3H]

Dihydroxyphenylethylamine (dopamine, DA), tritiated at the ring-2,5,6- position. Dihydroxyphenylethylamine is a neurotransmitter and is the primary endogenous ligand for dopamine receptors.
Price Range : 901.00 EUR - 2090.00 EUR

Rosiglitazone, DL- [3H]-

Tritiated DL-Rosiglitazone (Avandia). Rosiglitazone acts as a selective agonist at peroxisome proliferator-activated receptors (PPARs).
List Price : 1977.00 EUR

Methylspiperone, [N-Methyl-3H]-, 250µCi (9.25MBq)

Methylspiperone radioligand tritiated at the N-Methyl position. Methylspiperone is an antagonist at the 5-HT2A receptor and a selective dopamine D2 antagonist.
List Price : 2807.00 EUR

Nociceptin, [Leucyl-3,4,5-3H], 50µCi (1.85MBq)

Nociceptin, tritiated on the leucine residue. Nociceptin is the endogenous ligand for the nociceptin receptor (NOP, ORL-1).
List Price : 4542.00 EUR

3-INDOLYLACETIC ACID, [5-3H(N)]-

3-Indolyacetic acid tritiated at the 5 position. Indole-3-acetic acid (IAA, 3-IAA) is the most common, naturally occurring, plant hormone of the auxin class.
List Price : 2059.00 EUR

8-Hydroxy-DPAT, [Propyl-2,3-ring-1,2,3-3H]-

8-OH-DPAT radioligand tritiated at the 1,2,3 position on the propyl-2,3-ring. 8-OH-DPAT is a serotonin receptor agonist specific for the 5-HT1A and 5-HT7 receptors.
Price Range : 1688.00 EUR - 4285.00 EUR

Taurine, [2,2,3H]

Taurine, tritiated at the 2,2 position. Taurine acts as an agonist at glycine receptors.
Price Range : 1663.00 EUR - 5400.00 EUR

"Ligands" 1-50 of 125 Products and Services

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