PerkinElmer

Ligands

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Eliminate the need for antibodies and reduce assay time with direct detection using our radiolabeled ligands, which provide for sensitive and quantitative measurement of binding.

  • High specific activity — The majority of our 125I-labeled ligands are offered at maximum specific activity. This means virtually every molecule of ligand provided in the stock vial is radiolabeled. For tritiated ligands (3H ligands), pick a ligand with specific activity above 20 Ci/mmol – all of our tritiated ligands meets or exceeds these requirements.
  • High purity — We offer highly-pure radioligands for the highest specific signal with low background in binding assays.
  • High selectivity — Our broad portfolio of agonists and antagonists offers many options for choosing the most selective compound for your receptor.
  • Validated for receptor binding — all of our radioligand products are tested for receptor binding during development. Additionally, many of our radioligands are used to QC our GPCR and receptor cell lines and cell membrane products.

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Radioisotope
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  • 201-250 (57)

"Ligands" 1-50 of 119 Products and Services

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Adenosine 5 Triphosphate 250 µCi

MDL105,519, [3H]

Tritiated MDL 105,519. MDL 105,519 acts as a potent and selective antagonist at N-methyl-D-aspartate (NMDA) receptors.
List Price : 3771.00 EUR
Adenosine 5 Triphosphate 250 µCi

5-Hydroxytryptamine Creatinine Sulfate, [1,2-3H(N)]

5-Hydroxytryptamine Creatinine Sulfate (Serotonin, 5-HT), tritiated at the 1,2 position. 5-Hydroxytryptamine is a neurotransmitter and is the endogenous ligand for serotonin receptors.
Price Range : 1049.00 EUR - 2835.00 EUR
Adenosine 5 Triphosphate 250 µCi

Norepinephrine, Levo-[ring-2,5,6-3H]

Levo-Norepinephrine, tritiated on the ring group. Norepinephrine binds and activates adrenergic receptors, and is cleared by the norepinehprine transporter (NET).
Price Range : 1865.00 EUR - 11900.00 EUR
Adenosine 5 Triphosphate 250 µCi

Raclopride, [Methoxy-3H]

Raclopride, [Methoxy-3H]- will have fresh lot dates on the second Monday in March and September.
Price Range : 785.00 EUR - 6300.00 EUR
Adenosine 5 Triphosphate 250 µCi

Muscimol, 3-Hydroxy-5-Aminomethylisoxazole, [Methylene-3H(N)]

3H Muscimol radioligand. Muscimol acts as a potent selective agonist at GABAA receptors. It also acts as a partial agonist at GABAA-rho receptors. This product has a scheduled lot release for the second Monday in February and August. NOTE: NET574001MC will be obsolete soon.
List Price : 2465.00 EUR
Adenosine 5 Triphosphate 250 µCi

Kainic acid, [Isopropenyl-3H]

Kainic acid, tritiated on the isoproprenyl group. Kainic acid acts as an agonist at kainate glutamate receptors.
Price Range : 799.00 EUR - 7400.00 EUR
Adenosine 5 Triphosphate 250 µCi

Lysergic Acid Diethylamide, [N-Methyl-3H]-, 250µCi (9.25MBq)

Lysergic Acid Diethylamide (LSD), tritiated on the N-methyl group. LSD is a partial agonist of dopamine D2 receptors. It also binds most serotonin receptors (5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT5A, 5-HT5B and 5-HT6). This product has a scheduled lot release for the second Monday in April, August and December.
List Price : 2772.00 EUR
Adenosine 5 Triphosphate 250 µCi

Norepinephrine, Levo-[7-3H]

Levo-Norepinephrine, tritiated at the 7 position. Norepinephrine binds and activates adrenergic receptors, and is cleared by the norepinehprine transporter (NET). This product has a scheduled lot release for the third Monday in July.
Price Range : 1682.00 EUR - 12800.00 EUR
Adenosine 5 Triphosphate 250 µCi

Strychnine, [Benzene-Ring-3H]-, 250µCi (9.25MBq)

Strychnine, tritiated on the benzene ring. Strychnine acts as an antagonist at glycine and acetylcholine receptors.
List Price : 3442.00 EUR
Adenosine 5 Triphosphate 250 µCi

RO 15-4513, [7,9-3H]-, 250µCi (9.25MBq)

Ro15-4513, tritiated at the 7,9 position. Ro15-4513 is a partial inverse agonist at GABAA receptors.
List Price : 3384.00 EUR
Adenosine 5 Triphosphate 250 µCi

Deltorphin II (2-D-Ala), [Tyrosyl-3,5-3H]

Deltorphin II, tritiated at the tyrosyl-3,5 position. Deltorphin II is a selective δ opioid receptor (DOPR) agonist.
Price Range : 1284.00 EUR - 5400.00 EUR
Adenosine 5 Triphosphate 250 µCi

Escitalopram, [N-methyl-3H]-

Escitalopram (Cipralex), tritiated at the N-methyl position. Escitalopram is a selective serotonin reuptake inhibitor (SSRI) with high selectivity for the serotonin transporter (SERT) compared to the norepinephrine transporter (NET).
List Price : 6300.00 EUR
Adenosine 5 Triphosphate 250 µCi

Astemizole, [O-Methyl-3H]

Astemizole (Hismanal) tritiated at the O-methyl group. Atemizole is an antagonist of the histamine H1-receptor and has been shown to block hERG potassium channels.
Price Range : 986.00 EUR - 9800.00 EUR
Adenosine 5 Triphosphate 250 µCi

Dihydroxyphenylethylamine (Dopamine), 3,4-[Ring-2,5,6-3H]

Dihydroxyphenylethylamine (dopamine, DA), tritiated at the ring-2,5,6- position. Dihydroxyphenylethylamine is a neurotransmitter and is the primary endogenous ligand for dopamine receptors.
Price Range : 901.00 EUR - 2090.00 EUR

WAY100635, [METHOXY-3H], 250 uCi

WAY-100635, tritiated on the methoxy group. WAY-100635 acts as an antagonist at serotonin 5-HT1A receptors. It also acts as an agonist at dopamine D4 receptors. WAY-100635 is on a scheduled release and is available on the second Monday in February and August. 
List Price : 5100.00 EUR
Adenosine 5 Triphosphate 250 µCi

WIN 35428, [N-Methyl-3H]

WIN 35428 [(–)-2-β-Carbomethoxy-3-β-(4-fluorophenyl)tropane], tritiated on the N-methyl group. WIN 35428 acts as an antagonist at dopamine transporters (DATs).
Price Range : 992.00 EUR - 7100.00 EUR
Adenosine 5 Triphosphate 250 µCi

Verapamil Hydrochloride, [N-Methyl-3H]

Verapamil hydrochloride, tritiated on the N-methyl group. Verapamil acts as a calcium channel blocker (CCB).
Price Range : 957.00 EUR - 3619.00 EUR
Adenosine 5 Triphosphate 250 µCi

Methyl-4-Phenylpyridinium Acetate, N-[Methyl-3H]-, MPP (+)

N-Methyl-4-phenylpyridinium (MPP+) acetate, tritiated on the methyl group. MPP+ is a substrate for the organic cation ion transporter (OCT), the dopamine transporter (DAT), the norepinephrine transporter (NET), and the serotonin transporter (SERT).
Price Range : 720.00 EUR - 1919.00 EUR
Adenosine 5 Triphosphate 250 µCi

Histamine Dihydrochloride, [Ring, Methylenes-3H(N)]

Histamine dihydrochloride, tritiated on the ring and methylene groups. Histamine is an endogenous agonist of histamine receptors.
Price Range : 1519.00 EUR - 3305.00 EUR
Adenosine 5 Triphosphate 250 µCi

Enkephalin, [Tyrosyl-2,6-3H(N)]- (2-D-Penicillamine, 5-D-Penicillamine) (DPDPE)

2-D-Penicillamine, 5-D-Penicillamine (DPDPE), tritiated on the tyrosyl group. Cyclic peptide, sequence: Tyr-D-Pen-Gly-Phe-D-Pen-OH. DPDPE is a synthetic enkephalin opioid peptide that acts as an agonist at delta opiate receptors (δ-opioid receptor, DOR). This product has a scheduled lot release for the second Monday in February and August.
Price Range : 1366.00 EUR - 6600.00 EUR
Adenosine 5 Triphosphate 250 µCi

SCH 23390, [N-Methyl-3H]

SCH-23390 (halobenzazepine), tritiated on the N-methyl group. SCH-23390 acts as an antagonist at the dopamine D1 receptor.
Price Range : 732.00 EUR - 4003.00 EUR
Adenosine 5 Triphosphate 250 µCi

(+/-) Epibatidine, [5,6-Bicycloheptyl-3H]

(+/-)-Epibatidine radioligand tritiated at the 5,6-biocycloheptyl position. Epibatidine has analgesic activities, has been shown to function as an agonist at nicotinic acetylcholine receptors, and has been shown to bind muscarinic and serotonin 5-HT3 receptors.
Price Range : 2423.00 EUR - 5800.00 EUR
Adenosine 5 Triphosphate 250 µCi

Cytisine HCl, [3,5-3H(N)]

Cytisine HCl, [3,5-3H(N)]- will have fresh lot dates on the second Monday in April.
Price Range : 838.00 EUR - 3011.00 EUR
Adenosine 5 Triphosphate 250 µCi

U-69,593, [Phenyl-3,4-3H]

U-69,593, tritiated at the phenyl-3,4 position. U-69,593 is a selective κ1-opioid receptor agonist.
Price Range : 973.00 EUR - 3170.00 EUR
Adenosine 5 Triphosphate 250 µCi

Oxytocin, [Tyrosyl-3,5-3H]-, 50µCi (1.85MBq)

Oxytocin, tritiated on the tyrosyl group. Oxytocin is a neurotransmitter that binds and activates oxytocin receptors.
List Price : 1811.00 EUR
Adenosine 5 Triphosphate 250 µCi

Ro 15-1788, [N-Methyl-3H]

Ro 15-1788 (flumazenil), tritiated on the N-methyl group. Ro 15-1788 acts as a selective benzodiazepine antagonist.
Price Range : 913.00 EUR - 6800.00 EUR

QUISQUALIC ACID, [3H]

Quisqualic acid, tritiated. Quisqualic acid acts as an agonist at AMPA receptors, kainate receptors, and group 1 metabotropic glutamate receptors.
List Price : 2841.00 EUR

Butyl Bicyclophosphorothionate, Tertiary-[35S]

Tertiary-Butylbicyclophosphorothionate (TBPS), radiolabeled with S-35. TBPS is a GABAA receptor antagonist.
Price Range : 2819.00 EUR - 4978.00 EUR
Adenosine 5 Triphosphate 250 µCi

Paroxetine, [Phenyl-6'-3H]

Paroxetine (Paxil), tritiated at the phenyl-6' position. Paroxetine is a selective serotonin reuptake inhibitor (SSRI). This product has a scheduled lot release for the first Monday in May and November.
Price Range : 873.00 EUR - 3887.00 EUR
Adenosine 5 Triphosphate 250 µCi

DAMGO, [Tyrosyl-3,5-3H(N)]

DAMGO, tritiated at the tyrosyl 3,5 poisition. DAMGO is a synthetic opioid analog with high specificity for the μ-opioid receptor.
Price Range : 2420.00 EUR - 6300.00 EUR
Adenosine 5 Triphosphate 250 µCi

Dihydroalprenolol Hydrochloride, Levo-[Ring, Propyl-3H(N)]

Dihydroalprenolol hydrochloride, tritiated on the ring propyl group. Dihydroalprenolol (DHA) is an alprenolol derivative that binds to beta-adrenergic receptors and acts as a beta-adrenergic blocker.
Price Range : 1378.00 EUR - 3133.00 EUR
Adenosine 5 Triphosphate 250 µCi

CGS 21680, [Carboxyethyl-3H(N)]

CGS 21680, tritiated at the carboxyethyl group. CGS 21680 acts as an agonist for the adenosine A2A receptor, but can also bind adenosine A1 and A3.
Price Range : 2577.00 EUR - 6200.00 EUR
Adenosine 5 Triphosphate 250 µCi

Imipramine Hydrochloride, [Benzene ring-3H(N)]-, 250µCi (9.25MBq)

Imipramine hydrochloride, tritiated on the benzene ring. Imipramine is believed to act as an antagonist at certain serotonin, histamine, and cholinergic receptors.
List Price : 2072.00 EUR
Adenosine 5 Triphosphate 250 µCi

CCK-8(SULPHATED), [3H]PROPIONY, 50 µCi

CCK-8, tritiated at the propionyl position. Sulphated CCK8 is a peptide hormone that can bind both cholecystokinin B and cholecystokinin A receptors.
List Price : 2386.00 EUR
Adenosine 5 Triphosphate 250 µCi

Pyrilamine (Mepyramine), [pyridinyl 5-3H]-, 250µCi (9.25MBq)

Pyrilamine (Mepyramine), tritiated at the pyridinyl 5 position. Pyrilamine acts as an antagonist at the histamine H1 receptor.
List Price : 2212.00 EUR
Adenosine 5 Triphosphate 250 µCi

Rosiglitazone, DL- [3H]-

Tritiated DL-Rosiglitazone (Avandia). Rosiglitazone acts as a selective agonist at peroxisome proliferator-activated receptors (PPARs).
List Price : 1977.00 EUR
Adenosine 5 Triphosphate 250 µCi

5-Hydroxy tryptamine, [3H]

5-hydroxytryptamine (5-HT, or serotonin) labeled with tritium. It is a naturally occurring neurotransmitter which is tied to positive mood, certain involuntary muscle control, and countless other functions.
Price Range : 865.00 EUR - 3172.00 EUR
Adenosine 5 Triphosphate 250 µCi

8-Hydroxy-DPAT, [Propyl-2,3-ring-1,2,3-3H]-

8-OH-DPAT radioligand tritiated at the 1,2,3 position on the propyl-2,3-ring. 8-OH-DPAT is a serotonin receptor agonist specific for the 5-HT1A and 5-HT7 receptors.
Price Range : 1688.00 EUR - 4285.00 EUR
Adenosine 5 Triphosphate 250 µCi

Bradykinin, [2,3-Prolyl-3,4-3H(N)]

Bradykinin, tritiated at the 2,3-prolyl-3,4 position. Bradykinin is the endogenous ligand that activates bradykinin B1 and B2 receptors.
Price Range : 2476.00 EUR - 5700.00 EUR
Adenosine 5 Triphosphate 250 µCi

SR141716A, [3H]

Tritiated SR141716A (rimonabant; Acomplia; Zimulti). SR141716A acts as an inverse agonist at the cannabinoid CB1 receptor.
List Price : 3492.00 EUR
Adenosine 5 Triphosphate 250 µCi

Diprenorphine [15,16-3H]

Diprenorphine (Revivon; M5050; diprenorfin), tritiated at the 15,16- position. Diprenorphine acts as a non-selective antagonist at opioid receptors.
Price Range : 838.00 EUR - 1743.00 EUR
Adenosine 5 Triphosphate 250 µCi

Taurine, [2,2,3H]

Taurine, tritiated at the 2,2 position. Taurine acts as an agonist at glycine receptors.
Price Range : 1663.00 EUR - 5400.00 EUR
Adenosine 5 Triphosphate 250 µCi

Enkephalin (2-D-Alanine-5-D-Leucine), [Tyrosyl-3,5-3H(N)]-, 250µCi (9.25MBq)

DADLE, tritiated on the tyrosyl group. Peptide sequence: Tyr-D-Ala-Gly-L-Phe-D-Leu. DADLE is a synthetic enkephalin analog considered selective for the delta opioid receptor, but has been shown to bind the mu opioid receptor as well.
List Price : 2368.00 EUR
Adenosine 5 Triphosphate 250 µCi

Citalopram, [N-Methyl-3H]

Citalopram, tritiated at the N-methyl group. Citalopram is a selective serotonin reuptake inhibitor (SSRI) antidpressant drug, and has been shown to block the serotonin transporter (SERT, 5-HTT).
Price Range : 1559.00 EUR - 3403.00 EUR
Adenosine 5 Triphosphate 250 µCi

SB-269970, [3H]

Tritiated SB-269970. SB-269970 is believed to act as a selective serotonin 5-HT7 antagonist, or possibly an inverse agonist.
List Price : 4590.00 EUR
Adenosine 5 Triphosphate 250 µCi

Acetylcholine Iodide, [acetyl-3H], 1mCi (37MBq)

Acetylcholine (Ach) radioligand tritiated on the acetyl group. Acetylcholine is a neurotransmitter and the endogeous ligand that binds to and activates muscarinic and nicotinic acetylcholine receptors.
List Price : 869.00 EUR
Adenosine 5 Triphosphate 250 µCi

Flunitrazepam, [Methyl-3H]

Flunitrazepam (Rohypnol), tritiated on the methyl group. Flunitrazepam is a benzodiazepine and acts as an agonist at GABAA (γ-aminobutyric acid) receptors.
Price Range : 744.00 EUR - 7500.00 EUR
Adenosine 5 Triphosphate 250 µCi

(-)-CGP-12177, [5,7-3H]

(-)-CGP-12177 radioligand tritiated at the 5,7 position. CGP-12177 acts as an antagonist at the β1- and β2-adrenoceptors and a partial agonist at β3-adrenoceptors.
Price Range : 720.00 EUR - 1793.00 EUR
Adenosine 5 Triphosphate 250 µCi

Oxotremorine-M Acetate, [Methyl-3H]-,>97%, 250µCi (9.25MBq)

Oxotremorine-M acetate, tritiated on the methyl group. Oxotremorine-M acts as a selective agonist at muscarinic acetylcholine receptors.
List Price : 3220.00 EUR
Adenosine 5 Triphosphate 250 µCi

Vinblastine Sulphate, [G-3H]

Vinblastine sulphate, tritiated. Vinblastine binds to tubulin and inhibits microtubule formation.
Price Range : 2153.00 EUR - 8000.00 EUR

"Ligands" 1-50 of 119 Products and Services

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