PerkinElmer

Inflammation Research

OF

Inflammation is a natural marker for bodily health, and abnormal inflammatory response is indicated in an increasingly wide net of diseases and disorders, from cardiovascular disease and diabetes to major depression. Detect and quantitate inflammatory biomarkers with our wide range of in vivo, cellular, in situ, and biochemical inflammation research products.

Our products for inflammation research include:

  • LANCE® TR-FRET technology for detection and quantitation of cytokines and other biomarkers
  • AlphaLISA® Immunoassay kits for detection and quantitation of cytokines and other biomarkers
  • DELFIA® (dissociation-enhanced lanthanide fluorescence immunoassay) TRF technology
  • Cellular, tissue, and in vivo imaging systems
  • Near-infrared (NIR) fluorescent and chemiluminescent in vivo imaging agents
  • Target-specific radiolabeled ligands and receptor-transfected cell lines and membranes
  • High content screening

This product portfolio meets the demands of many types of inflammation research:

  • Quick and specific detection of inflammatory biomarkers in human and animal samples, including pro-inflammatory cytokines and chemokines like IL-8, IL-6, IL-2, IFN gamma, and TNF alpha and beta.
  • Monitoring acute and pulmonary inflammation and therapeutic treatment in animal models in real time
  • Phenotypic analysis
  • Targeted studies in various sample types with high sensitivity and specificity

  • Products and Services

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  • Accessories (44)
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  • High biotin samples (7)
  • Immunohistochemistry (IHC) (23)
  • In situ hybridization (ISH) (23)
  • In vivo imaging (1)
  • Protein Analysis & Detection (164)
Assay points(200-50,000)
  • 100 (51)
  • 10000 (28)
  • 500 (116)
  • 5000 (86)
Assay Target
  • CCL1 (1)
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  • Cyr61 (1)
  • Fibrinogen (2)
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  • IFN-λ2 (4)
  • IFNα (2)
  • IFNγ (10)
  • IL-1RA (4)
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  • IL-23A (2)
  • IL-31 (2)
  • IL-6 (3)
  • IL10 (2)
  • IL11 (2)
  • IL12 (8)
  • IL13 (3)
  • IL15 (1)
  • IL17A (8)
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  • TNFα (10)
  • TSLP (4)
Assay Target Class
  • Cytokine (146)
  • GPCR (45)
  • Protein (21)
Assay Validated
  • Binding (23)
  • Calcium Fluorescence (7)
  • Calcium Luminescence (19)
  • cAMP (16)
  • Downstream Phosphorylation (7)
  • GTPγS (8)
  • Inositol Phosphate (2)
Automation Compatible
  • Yes (178)
Detection Method
  • Alpha (132)
  • Chromogenic (6)
  • Fluorescence (27)
  • Time-Resolved Fluorescence (TRF) (24)
  • TR-FRET (24)
  • Transmission (2)
Experimental Type
  • In vitro (129)
Fluorescent Agent Type
  • Activatable (9)
  • Cell labeling (2)
  • Targeted (1)
  • Vascular (5)
Fluorophore
  • Coumarin (1)
  • Cy3 (8)
  • Cy5 (4)
  • Fluorescein (6)
  • TMR (5)
Format
  • Microplates (152)
  • Slides (23)
Host Cell
  • CHO-K1 (42)
  • HEK293 (3)
Imaging Modality
  • Chemilumiluminescence (2)
  • Fluorescence (16)
  • High Content (2)
  • microCT Imaging (1)
  • Optical Imaging (6)
Product Brand Name
  • AequoScreen (11)
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  • AlphaPlex (4)
  • Ancillary Products (2)
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  • Cat B FAST (2)
  • FolateRSense (1)
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  • TSA (12)
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  • VivoTrack (2)
  • XenoLight (2)
Receptor Type
  • Anaphylatoxin (1)
  • Bradykinin (4)
  • Chemokine (28)
  • Histamine (10)
  • Prostanoid (2)
Target Species
  • Bovine (6)
  • Cynomolgus (4)
  • Human (123)
  • Monkey (2)
  • Mouse (33)
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  • Rat (1)
Therapeutic Area
  • Angiogenesis (14)
  • Arthritis (13)
  • Atherosclerosis (9)
  • Cancer (2)
  • Cardiovascular (9)
  • Central Nervous System (3)
  • Gastrointestinal (4)
  • Inflammation (220)
  • Metabolic (4)
  • Oncology/Cancer (13)
  • Pain (8)
  • Vascular disease (5)
Volume Capacity
  • 150 µL (2)

"Inflammation" 1-50 of 328 Products and Services

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IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina LT In Vivo Imaging System

The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
IVIS Spectrum In Vivo Imaging System

IVIS SpectrumBL High-Throughput In Vivo Optical Imaging System

The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina III In Vivo Imaging System

The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
Opera Phenix HCS Systems

Opera Phenix High-Content Screening System

The Opera Phenix High Content Screening System is the premier confocal solution for today's most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera® High Content Screening System, the Opera Phenix is designed for high-throughput, phenotypic screening and assays involving complex disease models, such as live cells, primary cells and microtissues.
Operetta CLS HCS System

Operetta CLS High-Content Analysis System

Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS lets you find even subtle phenotypic changes.
IVIS SpectrumCT 2D/3D Optical/CT In Vivo Imaging System

IVIS SpectrumCT In Vivo Imaging System

The IVIS® SpectumCT preclinical in vivo imaging system expands upon the versatility of the IVIS Spectrum by offering 2D and 3D imaging capabilities but includes integrated low-dose microCT ideal for longitudinal studies. The system provides researchers with greater insights into complex biological systems by enabling simultaneous molecular and anatomical non-invasive imaging in animal models.
IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

IVIS Lumina XRMS In Vivo Imaging System

Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.
IVIS Spectrum In Vivo Imaging System

IVIS Spectrum In Vivo Imaging System

The IVIS® Spectrum in vivo imaging system combines 2D optical and 3D optical tomography in one platform. The system uses leading optical technology for preclinical imaging research and development ideal for non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
AlphaLISA immunoassay kits

IL-8 (human) AlphaLISA Biotin-Free Detection Kit

The AlphaLISA Human IL8 Biotin-Free Detection Kit is designed for the quantitative detection of human IL-8 in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit uses anti-DIG (anti-Digoxin) Donor beads instead of streptavidin Donor beads, which makes the kit compatible with high-biotin culture media and other sample types that contain high levels biotin (including brain/liver tissue extracts, milk and eggs).
Price Range : 721.00 EUR - 10400.00 EUR

IL-1α (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human IL-1α Detection Kit is designed for detection and quantitation of human interleuukin-1α in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 826.00 EUR - 11000.00 EUR

IL-10 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Interleukin-10 (IL-10) Detection Kit is designed for detection and quantitation of human IL-10 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1578.00 EUR - 10500.00 EUR
Receptor-expressing cell lines

cAMPZen Frozen cells, Chemokine CCR7, Human Recombinant, CHO-K1

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 533.00 EUR
alphaimmunoassay1

IL-1β (human) AlphaLISA Detection Kit

The AlphaLISA® Human Interleukin-1β (IL1β) Detection Kit is designed for detection and quantitation of human IL-1β in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1578.00 EUR - 10500.00 EUR
AlphaLISA immunoassay kits

IL-17A (human) AlphaLISA Biotin-Free Detection Kit

AlphaLISA Human IL-17A Biotin-Free Detection Kit is designed for the quantitative detection of human IL-17A in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit uses anti-DIG (anti-Digoxin) Donor beads instead of streptavidin Donor beads, which makes the kit compatible with high-biotin culture media and other sample types that contain high levels biotin.
Price Range : 721.00 EUR - 10400.00 EUR
AlphaLISA immunoassay kits

IL-17A (mouse/rat) AlphaLISA Biotin-free Detection Kit

The AlphaLISA Mouse/Rat IL-17A Biotin-Free Detection Kit is designed for the quantitative detection of mouse or rat IL-17 (IL-17A) in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit uses anti-DIG (anti-Digoxin) Donor beads instead of streptavidin Donor beads, which makes the kit compatible with high-biotin culture media and other sample types that contain high levels biotin (including brain/liver tissue extracts, milk and eggs).
Price Range : 476.00 EUR - 10400.00 EUR
Amplification Diluent

TSA Tetramethylrhodamine Tyramide Reagent Pack, Reagents for 100-300 Slides

TSA® tetramethylrhodamine (TMR) reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.
List Price : 690.00 EUR

IFN-α (human) AlphaLISA Detection Kit

The AlphaLISA® Human Interferon-alpha (IFN-α) Detection Kit is designed for detection and quantitation of human IFN-α in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay. The analyte in this kit consists of the IFN-α 2b subtype.
Price Range : 1578.00 EUR - 10500.00 EUR
Receptor-expressing cell lines

Chemokine CX3CR1 AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
LANCE Detection Kit

CCL3/MIP1α (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human CCL3/MIP1α Detection Kit is designed for detection and quantitation of human CCL3 (MIP1α) in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 826.00 EUR - 11000.00 EUR
AlphaLisa Analyte 2

PDGF (BB dimer) (human), lyophilized (AlphaLISA)

Human PDGF (BB homodimer) standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA human PDGF Detection Kit, but can also be ordered separately.
List Price : 306.00 EUR
Receptor-expressing cell lines

Chemokine CXCR2 AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.

Heme oxygenase 1 AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human heme oxygenase 1 (HO-1) enables the quantitative determination of human HO-1 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 449.00 EUR - 9800.00 EUR
alphaimmunoassay1

GM-CSF (human) AlphaLISA Detection Kit

The AlphaLISA® Human Granulocyte/Macrophage Colony-Stimulating Factor (GM-CSF) Detection Kit is designed for detection and quantitation of human GM-CSF in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1578.00 EUR - 10500.00 EUR

Fibrinogen (human) AlphaLISA Detection Kit

The AlphaLISA® Human Fibrinogen Detection Kit is designed for detection and quantitation of Human fibrinogen in human serum, plasma, and cell culture supernatants using a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 462.00 EUR - 10400.00 EUR
AlphaLISA immunoassay kits

MCP2 (mouse) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for mouse MCP2 enables the quantitative determination of mouse monocyte chemoattractant protein 2 (MCP2; CCL8) in buffer and serum using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 1211.00 EUR - 11500.00 EUR

IL-1RA (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human IL-1RA Detection Kit is designed for detection and quantitation of human interleukin-1RA in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 925.00 EUR - 12300.00 EUR
AlphaLISA immunoassay kits

IL-17A (mouse/rat) AlphaLISA Detection Kit

The AlphaLISA® Mouse/Rat Interleukin-17 (IL-17A) Detection Kit is designed for detection and quantitation of mouse or rat IL-17A in buffered solution, or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1578.00 EUR - 10500.00 EUR
AlphaLISA immunoassay kits

IL-1α (bovine) AlphaLISA Detection Kit

The AlphaLISA immunoassay kit for detection and quantitation of bovine IL1α in serum, cell culture supernatants, and other sample types allows for fast, reproducible, and sensitive detection without the need for time-consuming wash steps or complicated assay development.
Price Range : 669.00 EUR - 10700.00 EUR

IL-2 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human IL-2 Detection Kit is designed for detection and quantitation of human IL-2 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay. It is a fast and simple alternative to a human IL-2 ELISA kit.
Price Range : 826.00 EUR - 11000.00 EUR

IL-25 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human IL-25 enables the quantitative determination of human interleukin 25 (IL-25) in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 623.00 EUR - 14900.00 EUR
Receptor-expressing cell lines

Bradykinin rB1AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
AlphaLISA immunoassay kits

IL-12 (bovine) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for bovine IL-12 enables the quantitative determination of bovine IL-12 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 623.00 EUR - 18700.00 EUR
AlphaPlex Terbium immunoassay kits

AlphaPlex-545 Human IL1β Detection Kit

The AlphaPlex™ 545 Human IL1β Detection Kit is designed for the quantitative determination of human IL1β together with another analyte (AlphaLISA) in serum, buffered solution or cell culture medium using a homogeneous assay.
Price Range : 610.00 EUR - 10400.00 EUR
TSA Coumarin System (100-300 slides)

TSA Coumarin System, for 100-300 Slides

TSA® coumarin detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra coumarin in the localized area of the probe or antibody.
List Price : 864.00 EUR

IL-11 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Interleukin 11 (IL-11) Detection Kit is designed for detection and quantitation of IL-11 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1578.00 EUR - 10500.00 EUR

CXCL4/PF4 (Human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for CXCL4/PF4 enables the quantitative determination of CXCL4/PF4 in human serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps). The assay shows minumum cross-reactivity with mouse CXCL4/PF4 and human CXCL4L1/PF4V.
Price Range : 641.00 EUR - 19200.00 EUR
Receptor-expressing cell lines

AequoZen FroZen cells, Chemokine CCR10, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 845.00 EUR
AlphaLISA immunoassay kits

PDGF (BB dimer) (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human PDGF (BB homodimer) enables the quantitative determination of human platelet-derived growth factor (PDGF) in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 623.00 EUR - 14900.00 EUR
alphaimmunoassay1

IL-2 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Interleukin-2 (IL2) Detection Kit is designed for detection and quantitation of human IL-2 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1578.00 EUR - 10500.00 EUR
AlphaLISA immunoassay kits

CXCL9/MIG (human) AlphaLISA Detection Kit

The AlphaLISA® Human C-X-C Motif Chemokine 9 / Monokine Induced by Gamma Interferon (CXCL9 / MIG) Detection Kit is designed for detection and quantitation of human CXCL9/MIG in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 3023.00 EUR - 23600.00 EUR
AlphaLisa Analyte 2

IL-17F (human) Iyophilized (AlphaLISA)

Human IL17F standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA IL17F Detection Kit, but can be ordered separately.
List Price : 316.00 EUR
LANCE Detection Kit

IL-5 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human IL-5 Detection Kit is designed for detection and quantitation of human interleuukin-5 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 826.00 EUR - 11000.00 EUR

IL-11 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human IL-11 Detection Kit is designed for detection and quantitation of human interleukin-11 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 826.00 EUR - 11000.00 EUR
AlphaLISA immunoassay kits

IL-6 (monkey) AlphaLISA Detection Kit, 500 Assay Points

The AlphaLISA® immunoassay kit for monkey IL-6 enables the quantitative determination of cynomolgus monkey interleukin-6 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 623.00 EUR - 18700.00 EUR
AlphaLisa Analyte 2

TSLP (human), lyophilized (AlphaLISA)

Human TSLP standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA human TSLP Detection Kit, but can also be ordered separately.
List Price : 306.00 EUR
AlphaLISA immunoassay kits

TSLP (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human TSLP enables the quantitative determination of human TSLP in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 623.00 EUR - 14900.00 EUR

Monocyte Chemoattractant Protein-1 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Monocyte Chemoattractant Protein-1 (CCL2 / MCP1) Detection Kit is designed for detection and quantitation of human CCL2/MCP1 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1578.00 EUR - 10500.00 EUR
LANCE Detection Kit

IL-31 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human IL-31 Detection Kit is designed for detection and quantitation of human interleukin-31 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 802.00 EUR - 10700.00 EUR
AlphaLisa Analyte 2

CXCL12/SDF-1 (human), liquid (AlphaLISA)

Human CXCL12 (SDF-1) standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA human CXCL12 Detection Kit, but can also be ordered separately.
List Price : 242.00 EUR
AlphaLISA immunoassay kits

IFN-λ2 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human interferon lambda-2 (IFN-λ2) enables the quantitative determination of human IFN-λ2 in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 449.00 EUR - 9800.00 EUR

"Inflammation" 1-50 of 328 Products and Services

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