PerkinElmer

Inflammation Research

OF

Inflammation is a natural marker for bodily health, and abnormal inflammatory response is indicated in an increasingly wide net of diseases and disorders, from cardiovascular disease and diabetes to major depression. Detect and quantitate inflammatory biomarkers with our wide range of in vivo, cellular, in situ, and biochemical inflammation research products.

Our products for inflammation research include:

  • LANCE® TR-FRET technology for detection and quantitation of cytokines and other biomarkers
  • AlphaLISA® Immunoassay kits for detection and quantitation of cytokines and other biomarkers
  • DELFIA® (dissociation-enhanced lanthanide fluorescence immunoassay) TRF technology
  • Cellular, tissue, and in vivo imaging systems
  • Near-infrared (NIR) fluorescent and chemiluminescent in vivo imaging agents
  • Target-specific radiolabeled ligands and receptor-transfected cell lines and membranes
  • High content screening

This product portfolio meets the demands of many types of inflammation research:

  • Quick and specific detection of inflammatory biomarkers in human and animal samples, including pro-inflammatory cytokines and chemokines like IL-8, IL-6, IL-2, IFN gamma, and TNF alpha and beta.
  • Monitoring acute and pulmonary inflammation and therapeutic treatment in animal models in real time
  • Phenotypic analysis
  • Targeted studies in various sample types with high sensitivity and specificity

  • Products & Services

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Product Type
  • Accessories (44)
  • Consumables (2)
  • Instruments (8)
  • Reagents (267)
  • Software and Informatics (7)
Assay Target
  • CCL1 (1)
  • CCL18 (1)
  • CCL2 (3)
  • CCL3 (3)
  • CCL4 (1)
  • CCL5 (3)
  • CCL8 (1)
  • CRP (1)
  • CXCL1 (2)
  • CXCL1/GROα (2)
  • CXCL10 (3)
  • CXCL12 (2)
  • CXCL13 (4)
  • CXCL4/PF4 (2)
  • CXCL9 (3)
  • Cyr61 (1)
  • Fibrinogen (2)
  • G-CSF (1)
  • GM-CSF (2)
  • HO-1 (2)
  • HO-2 (2)
  • HVEM (2)
  • IFN-λ2 (4)
  • IFNα (2)
  • IFNγ (10)
  • IL-1RA (4)
  • IL-23 (2)
  • IL-23A (2)
  • IL-31 (2)
  • IL-6 (3)
  • IL10 (2)
  • IL11 (2)
  • IL12 (8)
  • IL12/p70 (1)
  • IL13 (3)
  • IL15 (1)
  • IL17A (8)
  • IL17F (4)
  • IL18 (1)
  • IL18BP (2)
  • IL1α (4)
  • IL1β (7)
  • IL2 (4)
  • IL21 (2)
  • IL22 (1)
  • IL23 (1)
  • IL25 (4)
  • IL28B (4)
  • IL31 (1)
  • IL33 (4)
  • IL4 (6)
  • IL5 (4)
  • IL6 (7)
  • IL7 (1)
  • IL8 (3)
  • IP10 (2)
  • MCP2 (1)
  • MIP1α (2)
  • Osteoprotegerin (2)
  • PDGF (2)
  • Periostin (1)
  • SDF1 (2)
  • TNFα (10)
  • TSLP (4)
Target Species
  • Bovine (6)
  • Cynomolgus (4)
  • Human (122)
  • Monkey (2)
  • Mouse (33)
  • Ovine (2)
  • Porcine (4)
  • Rat (1)
Application
  • cAMP (10)
  • Drug Discovery & Development (12)
  • High biotin samples (7)
  • Immunohistochemistry (IHC) (23)
  • In situ hybridization (ISH) (23)
  • In vivo imaging (1)
  • Protein Analysis & Detection (163)
Therapeutic Area
  • Angiogenesis (14)
  • Arthritis (13)
  • Atherosclerosis (9)
  • Cancer (2)
  • Cardiovascular (9)
  • Central Nervous System (3)
  • Gastrointestinal (4)
  • Inflammation (219)
  • Metabolic (4)
  • Oncology/Cancer (13)
  • Pain (8)
  • Vascular disease (5)
Product Brand Name
  • AequoScreen (11)
  • AequoZen (8)
  • AlphaLISA (127)
  • AlphaPlex (4)
  • Ancillary Products (2)
  • cAMPZen (8)
  • Cat B FAST (2)
  • FolateRSense (1)
  • IVIS (6)
  • LANCE Ultra (44)
  • Membrane Target Systems (8)
  • MMPSense (3)
  • Opera Phenix (1)
  • Operetta (29)
  • Operetta CLS (9)
  • Operetta CLS AND Opera Phenix (9)
  • ProSense (3)
  • Superhance (1)
  • TSA (12)
  • TSA Plus (12)
  • ValiScreen (10)
  • VivoTrack (2)
  • XenoLight (2)
Detection Method
  • Alpha (132)
  • Chromogenic (6)
  • Fluorescence (27)
  • Time-Resolved Fluorescence (TRF) (24)
  • TR-FRET (24)
  • Transmission (2)
Receptor Type
  • Anaphylatoxin (1)
  • Bradykinin (4)
  • Chemokine (28)
  • Histamine (10)
  • Prostanoid (2)
Assay Validated
  • Binding (23)
  • Calcium Fluorescence (7)
  • Calcium Luminescence (19)
  • cAMP (16)
  • Downstream Phosphorylation (7)
  • GTPγS (8)
  • Inositol Phosphate (2)
Volume Capacity
  • 150 µL (2)
Fluorescent Agent Type
  • Activatable (9)
  • Cell labeling (2)
  • Targeted (1)
  • Vascular (5)
Fluorophore
  • Coumarin (1)
  • Cy3 (8)
  • Cy5 (4)
  • Fluorescein (6)
  • TMR (5)
Assay points(200-50,000)
  • 100 (52)
  • 10000 (28)
  • 500 (117)
  • 5000 (87)
Assay Target Class
  • Cytokine (147)
  • GPCR (45)
  • Protein (20)
Automation Compatible
  • Yes (178)
Experimental Type
  • In vitro (128)
Format
  • Microplates (151)
  • Slides (23)
Host Cell
  • CHO-K1 (42)
  • HEK293 (3)
Imaging Modality
  • Chemilumiluminescence (2)
  • Fluorescence (16)
  • High Content (2)
  • microCT Imaging (1)
  • Optical Imaging (6)
Length
  • 51-100 (7)
  • 101-200 (1)
Model Compatible With
  • Operetta (29)
  • Operetta CLS (8)
  • Operetta CLS AND Opera Phenix (9)
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"Inflammation" 1-50 of 328 Products & Services

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IVIS Spectrum In Vivo Imaging System

IVIS SpectrumBL High-Throughput In Vivo Optical Imaging System

The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
1000x1000_Operetta

Operetta CLS High-Content Analysis System

Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS lets you find even subtle phenotypic changes.
IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina III In Vivo Imaging System

The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina LT In Vivo Imaging System

The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
1000x1000_Opera_Phenix

Opera Phenix High-Content Screening System

The Opera Phenix High Content Screening System is the premier confocal solution for today's most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera® High Content Screening System, the Opera Phenix is designed for high-throughput, phenotypic screening and assays involving complex disease models, such as live cells, primary cells and microtissues.
IVIS Spectrum In Vivo Imaging System

IVIS Spectrum In Vivo Imaging System

The IVIS® Spectrum in vivo imaging system combines 2D optical and 3D optical tomography in one platform. The system uses leading optical technology for preclinical imaging research and development ideal for non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

IVIS Lumina XRMS In Vivo Imaging System

Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.
IVIS SpectrumCT 2D/3D Optical/CT In Vivo Imaging System

IVIS SpectrumCT In Vivo Imaging System

The IVIS® SpectumCT preclinical in vivo imaging system expands upon the versatility of the IVIS Spectrum by offering 2D and 3D imaging capabilities but includes integrated low-dose microCT ideal for longitudinal studies. The system provides researchers with greater insights into complex biological systems by enabling simultaneous molecular and anatomical non-invasive imaging in animal models.
AlphaLISA immunoassay kits

IL-7 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Interleukin 7 (IL7) Detection Kit is designed for detection and quantitation of human IL-7 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1645.00 EUR - 10900.00 EUR

Il-12 (p70) (human) AlphaLISA Detection Kit

The AlphaLISA® Human Interleukin 12 (p70) Detection Kit is designed for detection and quantitation of human IL-12 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1645.00 EUR - 10900.00 EUR
AlphaLISA immunoassay kits

IL-2 (human) AlphaLISA Biotin-Free Detection Kit

AlphaLISA Human IL2 Biotin-Free Detection Kit is designed for the quantitative detection of human IL-2 in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit uses anti-DIG (anti-Digoxin) Donor beads instead of streptavidin Donor beads, which makes the kit compatible with high-biotin culture media and other sample types that contain high levels biotin (including brain/liver tissue extracts, milk and eggs).
Price Range : 752.00 EUR - 10900.00 EUR
In vivo Fluorescent Agents

MMPSense 645 FAST Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
List Price : 556.00 EUR
In vivo Fluorescent Agents

ProSense 750 EX Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
List Price : 489.00 EUR
Receptor-expressing cell lines

AequoZen FroZen Cells, Chemokine CCR7, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 888.00 EUR
alphaimmunoassay1

IL-1β (human) AlphaLISA Detection Kit

The AlphaLISA® Human Interleukin-1β (IL1β) Detection Kit is designed for detection and quantitation of human IL-1β in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1645.00 EUR - 10900.00 EUR
alphaimmunoassay1

IL-2 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Interleukin-2 (IL2) Detection Kit is designed for detection and quantitation of human IL-2 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1645.00 EUR - 10900.00 EUR
AlphaLISA immunoassay kits

IL-17A (mouse/rat) AlphaLISA Biotin-free Detection Kit

The AlphaLISA Mouse/Rat IL-17A Biotin-Free Detection Kit is designed for the quantitative detection of mouse or rat IL-17 (IL-17A) in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit uses anti-DIG (anti-Digoxin) Donor beads instead of streptavidin Donor beads, which makes the kit compatible with high-biotin culture media and other sample types that contain high levels biotin (including brain/liver tissue extracts, milk and eggs).
Price Range : 497.00 EUR - 10900.00 EUR

CCL3/MIP-1α (human) AlphaLISA Detection Kit

The AlphaLISA® Human C-C Motif Chemokine 3 / Macrophage Inflammatory Protein-1alpha (CCL3 / MIP-1α) Detection Kit is designed for detection and quantitation of human CCL3/MIP-1α in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1757.00 EUR - 10900.00 EUR
AlphaLISA immunoassay kits

CYR61 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human cysteine rich angiogenic inducer 61 (CYR61) enables the quantitative determination of human Cyr61 in serum and cell culture media using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 788.00 EUR - 15100.00 EUR
Protein

IL-23A (human), lyophilized (LANCE)

Human IL-23A standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Human IL-23A Detection Kit, but can also be ordered separately.
List Price : 320.00 EUR
LANCE Detection Kit

IL-31 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human IL-31 Detection Kit is designed for detection and quantitation of human interleukin-31 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 836.00 EUR - 11100.00 EUR

CXCL13 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human CXCL13 enables the quantitative determination of human C-X-C Motif Chemokine Ligand 13 in serum and cell culture media using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 811.00 EUR - 11600.00 EUR
In vivo Fluorescent Agents

AngioSense 680EX Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.
List Price : 457.00 EUR
AlphaLISA immunoassay kits

IL-4 (rhesus) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for rhesus interleukin-4 (IL-4) enables the quantitative determination of rhesus IL-4 in buffered solution, cell lysates, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 468.00 EUR - 10300.00 EUR
AlphaLisa Analyte 2

PDGF (BB dimer) (human), lyophilized (AlphaLISA)

Human PDGF (BB homodimer) standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA human PDGF Detection Kit, but can also be ordered separately.
List Price : 320.00 EUR
PerkinElmer

Membrane Target Systems: Chemoattractant C5a (human varient) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from CHO-K1 cells stably-transfected with human chemoattractant C5a (human varient) receptor, 400 units.
List Price : 864.00 EUR
AlphaLisa Analyte 2

CXCL1/GROα (human), 0.01 µg, lyophilized (AlphaLISA)

Human CXCL1/GROα standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Human CXCL1/GROα Detection Kit, but can be ordered separately.
List Price : 267.00 EUR
Receptor-expressing cell lines

ValiScreen Chemokine CCR7 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.

IL-17 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Interleukin-17 (IL-17, IL17A) Detection Kit is designed for detection and quantitation of human IL-17 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1645.00 EUR - 10900.00 EUR
Receptor-expressing cell lines

cAMPZen FroZen cells, Prostanoid EP2, Human Recombinant, HEK293

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 537.00 EUR
AlphaLisa Analyte 2

IL-1RA (human), lyophilized (AlphaLISA)

Human IL-1RA standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Human IL-1RA Detection Kit, but can be ordered separately.
List Price : 260.00 EUR
PerkinElmer

Membrane Target Systems: Chemokine XCR1 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 864.00 EUR
In vivo Fluorescent Agents

Cat B 750 FAST Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.  
List Price : 567.00 EUR

Monocyte Chemoattractant Protein-1 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Monocyte Chemoattractant Protein-1 (CCL2 / MCP1) Detection Kit is designed for detection and quantitation of human CCL2/MCP1 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1645.00 EUR - 10900.00 EUR
AlphaLISA assay principle

Osteoprotegerin (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for total osteoprotegerin enables the quantitative determination of human osteoprotegerin in human serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 669.00 EUR - 20100.00 EUR
AlphaLisa Analyte 2

IL-31 (human), lyophilized (LANCE)

Human IL-31 standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Human IL-31 TR-FRET Detection Kit, but can also be ordered separately.
List Price : 252.00 EUR
TSA Fluorescein System

TSA Fluorescein System

TSA® fluorescein detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra fluorescein in the localized area of the probe or antibody.
Price Range : 507.00 EUR - 890.00 EUR
In vivo Fluorescent Agents

AngioSPARK 680 Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.
List Price : 636.00 EUR
Receptor-expressing cell lines

cAMPZen Frozen cells, Chemokine CCR7, Human Recombinant, CHO-K1

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 559.00 EUR

IL-17A (human) AlphaLISA Biotin-Free Detection Kit

AlphaLISA Human IL-17A Biotin-Free Detection Kit is designed for the quantitative detection of human IL-17A in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit uses anti-DIG (anti-Digoxin) Donor beads instead of streptavidin Donor beads, which makes the kit compatible with high-biotin culture media and other sample types that contain high levels biotin.
Price Range : 752.00 EUR - 10900.00 EUR
AlphaLISA assay principle

IL-31 (Human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for IL-31 enables the quantitative determination of human IL-31 in serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps). The assay shows no cross-reactivity with mouse IL31. Cross-reactivity with other species has not been tested.
Price Range : 669.00 EUR - 20100.00 EUR
Receptor-expressing cell lines

Chemokine CXCR2 AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
AlphaLisa Analyte 2

CXCL12/SDF-1 (human), liquid (AlphaLISA)

Human CXCL12 (SDF-1) standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA human CXCL12 Detection Kit, but can also be ordered separately.
List Price : 252.00 EUR
LANCE Detection Kit

TNFα (mouse) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Mouse TNFα Detection Kit is designed for detection and quantitation of mouse tumor necrosis factor α in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 861.00 EUR - 11400.00 EUR
Protein

IL17F (human), lyophilized (LANCE)

Human interleukin 17 (IL-17F) standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Human IL-17F Detection Kit, but can also be ordered separately.
List Price : 260.00 EUR
AlphaLISA immunoassay kits

IL-17A (mouse/rat) AlphaLISA Detection Kit

The AlphaLISA® Mouse/Rat Interleukin-17 (IL-17A) Detection Kit is designed for detection and quantitation of mouse or rat IL-17A in buffered solution, or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1645.00 EUR - 10900.00 EUR
Receptor-expressing cell lines

AequoZen FroZen Cells, Chemokine CX3CR1, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 888.00 EUR
Receptor-expressing cell lines

cAMPZen FroZen Cells, Histamine H2, Human Recombinant, CHO-K1

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 559.00 EUR
LANCE Detection Kit

IFN-γ (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human IFNγ Detection Kit is designed for detection and quantitation of human interferon gamma in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 861.00 EUR - 11500.00 EUR
AlphaLisa Analyte 2

IL-25 (mouse), liquid (AlphaLISA)

Mouse IL-25 standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA mouse IL-25 Detection Kit, but can also be ordered separately.
List Price : 320.00 EUR

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