PerkinElmer

GPCR

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Accelerate your research into G-protein-coupled receptors with integrated solutions for any GPCR target, including Gs-, Gq- and Gi-coupled receptors. Count on us to help you identify and monitor

  • Effects of GPCR pathway activation: intracellular calcium, cAMP, phospho-ERK, inositol phosphate
  • Reporter gene expression
  • Receptor ligand binding
  • GTP binding

Our state-of-the-art GPCR solutions portfolio is extensive and includes:

  • Scalable GPCR cellular imaging, detection instrumentation and liquid handling systems for radiometric fluorescence, luminescence or photometric detection
  • Optimized cell-based assay platforms
  • Versatile reagents—GPCR cell lines; frozen, ready-to-use cells; radioligands; ligands; cloned receptor membranes

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Product Type
  • Accessories (6)
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  • Reagents (106)
Application
  • cAMP (8)
  • Drug Discovery & Development (49)
  • Kinase (6)
  • Multiplexing (8)
  • Protein Analysis & Detection (12)
Assay Points
  • 100 (8)
  • 1000 (1)
  • 10000 (14)
  • 500 (13)
  • 50000 (14)
Assay Target
  • Akt1 (2)
  • Akt1/2 (1)
  • Akt1/2/3 (6)
  • cAMP (3)
  • CREB (2)
  • ERK1/2 (15)
Assay Target Class
  • GPCR (46)
  • Phosphoprotein (21)
  • Protein (6)
Assay Validated
  • Binding (35)
  • Calcium Fluorescence (4)
  • Calcium Luminescence (20)
  • cAMP (5)
  • Downstream Phosphorylation (4)
Automation Compatible
  • Yes (31)
Concentration
  • 1.0 - 10 mCi/mL (2)
  • 1.12 mCi/mL (2)
  • 171.9 µCi/mL (2)
  • 50 µCi/mL (1)
  • 83.8 µCi/mL (1)
  • 87.6 µCi/mL (1)
  • <1.0 µCi/mL (1)
Detection Method
  • Absorbance (5)
  • Alpha (29)
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  • Label-free (2)
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  • Radiometric (21)
  • Time-Resolved Fluorescence (TRF) (7)
  • TR-FRET (2)
Experimental type
  • In vitro (24)
Format
  • Microplates (27)
Host Cell
  • 1321N1 (2)
  • A9 (1)
  • CHO-K1 (27)
  • HEK293 (23)
  • HT29 (1)
  • L Cells (1)
  • U373 (1)
  • UC11 (1)
Label Position
  • Generally Labeled (1)
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  • Specifically Labeled (4)
Maximum Temperature (Celsius)
  • 40-50 (2)
  • 50-60 (2)
Molecular modification
  • Phosphorylation (14)
Product Brand Name
  • AequoScreen (6)
  • AequoZen (14)
  • Alpha SureFire Ultra Multiplex (8)
  • AlphaLISA SureFire Ultra (3)
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  • AlphaScreen SureFire (14)
  • cAMPZen (5)
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  • EnSpire (3)
  • EnVision (3)
  • LANCE (1)
  • LANCE Ultra (1)
  • Membrane Target Systems (32)
  • NEN Radiochemicals (5)
  • NEN Radiolabeled Ligands (16)
  • Victor (3)
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Radionuclide
  • 125I (16)
  • 3H (5)
Radioisotope
  • H-3 (5)
  • I-125 (16)
Receptor Type
  • 5-Hydroxytryptamine (1)
  • 5-Hydroxytryptamine (Serotonin) (4)
  • Adenosine (13)
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  • Vasoactive Intestinal Peptide (1)
  • Vasopressin (4)
Target Species
  • Human (11)
Therapeutic Area
  • Angiogenesis (1)
  • Cardiovascular (28)
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  • Inflammation (32)
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  • Renal (2)
Volume
  • 0-50 (43)
  • 201-250 (2)
  • 451-500 (6)
  • Over 500 (6)

"GPCR" 1-50 of 118 Products and Services

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EnSpire Multimode Plate Reader

EnSpire® Multimode Plate Reader is designed to meet the demands of multi-user research environments, providing high performance technology and flexibility for a range of applications without compromising sensitivity. Combine this with our expertise and portfolio of reagents, PerkinElmer offers an unrivaled solution to your application needs.

ViewLux uHTS Microplate Imager

The ViewLux® is the gold standard, ultra high-speed microplate imager, ideal for high throughput screening of compound libraries requiring the ultimate in speed, reliability and high quality data.
VictorX_ImageA_320px

VICTOR Multilabel Plate Reader

The next generation VICTOR X Multilabel Plate Reader platform delivers flexibility, speed and performance to research labs of all sizes.
EnVision_Alone_Left_Angle

EnVision Multilabel Plate Reader

The EnVision Multilabel Plate Reader provides exceptional speed, ultra-high throughput, and maximum sensitivity across all detection technologies. Tried and tested, the EnVision microplate reader gives you robust performance and reliable data for high throughput screening, time after time.

EnSpire Alpha Plate Reader

The EnSpire Alpha Plate Reader provides proven Alpha technology to your lab at an affordable price and from the Alpha detection leader.
EnSight multimode plate-reader

EnSight Multimode Plate Reader

The EnSight multimode plate reader combines labeled, label-free & image-based cytometry technologies in a single benchtop platform. Imaging & online data analysis is fast: a 384-well plate can be imaged in less than 5 mins. The system’s modular design, combined with workflow-based Kaleido data acquisition & analysis software, gives a truly versatile plate reader that gets users productive quickly.
PerkinElmer

Membrane Target Systems: Dopamine D1 (human) membrane preparation, in L cells cells. 400 Units.

Cell membranes prepared from L cells stably-transfected with human dopamine D1 receptor, 400 units.
List Price : 784.00 EUR
PerkinElmer

Membrane Target Systems: Neurokinin NK1 (human endogenous) membrane preparation, in UC11 cells. 400 Units.

Cell membranes prepared from UC11 cells with human neurokinin NK1 receptor, 400 units.
List Price : 784.00 EUR
PerkinElmer

Membrane Target Systems: Cannabinoid CB2 (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Cannabinoid CB2 receptor, in HEK-293 cells.
List Price : 784.00 EUR
PerkinElmer

Membrane Target Systems: Urotensin UR2 (GPR14) (mouse) membrane preparation

Cell membranes prepared from cells stably-transfected with human Urotensin UR2 (GPR14) receptor, in CHO-K1 cells.
List Price : 784.00 EUR

(+)-Pentazocine, [Ring-1,3-3H]-,250µCi (9.25MBq)

250 µCi quantities of [Ring-1, 3-3H]-(+)-Pentazocine are available for your research.
List Price : 2710.00 EUR
PerkinElmer

Membrane Target Systems: Nociceptin NOP (ORL1) (human) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from CHO-K1 cells stably-transfected with human Nociceptin NOP (ORL1) receptor, 400 units.
List Price : 784.00 EUR
Receptor-expressing cell lines

AequoZen frozen cells Starter Kit

AequoZen cells expressing the histamine H1 or the muscarinic M5 receptor for flash-luminescence assay.
List Price : 1358.00 EUR
Receptor-expressing cell lines

AequoZen FroZen cells, Parental, 1321N1

AequoScreen Parental cell stably expressing the mitochondrially targeted apoaequorin gene. GPCRs of your choice can be transiently or stably transfected into these cell lines, for luminescence calcium assays.
List Price : 735.00 EUR
PerkinElmer

Membrane Target Systems: Opioid Kappa (OP2) (human) membrane preparation, in HEK-293 cells. 400 Units.

Cell membranes prepared from HEK293 cells stably transfected with human opioid kappa (OP2) receptor, 400 units.
List Price : 784.00 EUR
PerkinElmer

AlphaScreen cAMP Detection Kit

AlphaScreen no-wash assay kit for quantitative detection of cAMP.
Price Range : 406.00 EUR - 13900.00 EUR
Receptor-expressing cell lines

AequoZen Frozen cells, Adenosine α2A, Human Recombinant, HEK293

Our frozen, irradiated AequoZen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 735.00 EUR

SB-269970, [3H]

250 µCi quantities of tritiated SB-269970 are available for your research.
List Price : 4173.00 EUR
PerkinElmer

LANCE Ultra cAMP Detection Kit

The LANCE® Ultra cAMP assay is a homogeneous time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay designed to measure cAMP produced upon modulation of adenylyl cyclase activity by G-protein coupled receptors (GPCRs).
Price Range : 544.00 EUR - 7100.00 EUR
Receptor-expressing cell lines

AequoZen FroZen cells, Parental, CHO-K1 (+Gαq/i5)

AequoScreen Parental cell stably expressing the mitochondrially targeted apoaequorin gene. GPCRs of your choice can be transiently or stably transfected into these cell lines, for luminescence calcium assays.
List Price : 735.00 EUR
PerkinElmer

Membrane Target Systems: Serotonin 5HT1a (human) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from cells stably-transfected with human serotonin 5HT1a receptor
List Price : 784.00 EUR
SureFire principle

AlphaScreen SureFire Akt 1/2 (p-Ser473) Assay Kit

The AlphaScreen® SureFire® p-Akt 1/2 (Ser473) assay is a sandwich immunoassay for quantitative detection of phospho-Akt 1/2 (phosphorylated on Ser473) in cellular lysates using Alpha Technology.
Price Range : 1504.00 EUR - 16200.00 EUR
AlphaLISA SureFire Ultra kits

AlphaLISA SureFire Ultra p-CREB (Ser133) Assay Kit

The AlphaLISA® SureFire® Ultra™ p-CREB (Ser133) assay is a sandwich immunoassay for quantitative detection of phospho-CREB (phosphorylated on Ser133) in cellular lysates using Alpha Technology.
Price Range : 493.00 EUR - 28600.00 EUR
List Price : 1353.00 EUR

Insulin (human, recombinant), [125I], 10 µCi

[125I]-Insulin (h) is suitable for the use in radioimmunoassay as well as receptor binding assay. [125I]-Insulin (h) is radioiodinated with no carrier added 125I using the LPO iodination procedure and is purified by reversed phase HPLC.
List Price : 1272.00 EUR
AlphaLISA SureFire Ultra kits

AlphaLISA SureFire Ultra p-ERK1/2 (Thr202/Tyr204) Assay Kit

The AlphaLISA® SureFire® Ultra™ p-ERK 1/2 (Thr202/Tyr204) assay is a sandwich immunoassay for quantitative detection of phospho-ERK 1/2 (phosphorylated on Thr202/Tyr204 in ERK1, or Thr185/Tyr187 in ERK2) in cellular lysates using Alpha Technology.
Price Range : 493.00 EUR - 28600.00 EUR
Receptor-expressing cell lines

AequoZen FroZen cells, Adenosine A1, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 735.00 EUR
Alpha SureFire Ultra Multiplex kits

Alpha SureFire Ultra Multiplex p-AKT(Ser473) (Eu) + p-ERK (Tb) Kit

The Alpha SureFire® Ultra Multiplex kits allow the rapid, sensitive, and quantitative detection of phosphoproteins from cells, combined with the measurement of another protein, phospho or total. This Alpha Multiplex measurement is carried out in the same assay plate well from a single sample of cell lysate, and is achieved by the use of two types of Alpha Acceptor beads that emit at distinct wavelengths (545nm and 615nm).
Price Range : 752.00 EUR - 43700.00 EUR
PerkinElmer

LANCE cAMP Detection Kit

LANCE® TR-FRET cAMP assay kit, for Gs- and Gi-coupled GPCR functional assays.
Price Range : 143.00 EUR - 6400.00 EUR
PerkinElmer

Membrane Target Systems: Opioid Delta (human) membrane preparation, in HEK-293 cells. 400 Units.

Cell membranes prepared from HEK293 cells stably-transfected with human opioid delta receptor, 400 units.
List Price : 784.00 EUR
PerkinElmer

Membrane Target Systems: Chemoattractant C5a (human varient) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from CHO-K1 cells stably-transfected with human chemoattractant C5a (human varient) receptor, 400 units.
List Price : 784.00 EUR
Receptor-expressing cell lines

AequoZen FroZen cells, Parental, CHO-K1 (+Gα16, medium level)

AequoScreen Parental cell stably expressing the mitochondrially targeted apoaequorin gene. GPCRs of your choice can be transiently or stably transfected into these cell lines, for luminescence calcium assays.
List Price : 735.00 EUR
PerkinElmer

Membrane Target Systems: Serotonin 5HT2c (human) membrane preparation, in HEK-293 cells. 400 Units.

Cell membranes prepared from HEK293 cells stably-transfected with human serotonin 5HT2c receptor, 400 units.
List Price : 784.00 EUR

(+)-Pentazocine, [Ring-1,3-3H]-, 25µCi (925kBq)

25 µCi quantities of [Ring-1, 3-3H]-(+)-Pentazocine are available for your research.
List Price : 833.00 EUR
PerkinElmer

Membrane Target Systems: Vasoactive Intestinal Polypeptide VIP membrane preparation

Cell membranes prepared from HT29 cells containing human endogenous Vasoactive Intestinal Polypeptide (VIP) receptor.
List Price : 821.00 EUR
Receptor-expressing cell lines

AequoZen FroZen cells, Parental, HEK293

AequoScreen Parental cell stably expressing the mitochondrially targeted apoaequorin gene. GPCRs of your choice can be transiently or stably transfected into these cell lines, for luminescence calcium assays.
List Price : 735.00 EUR
SureFire principle

AlphaScreen SureFire Akt 1 (p-Ser473) Assay Kit

The AlphaScreen® SureFire® p-Akt1 (Ser473) assay is a sandwich immunoassay for quantitative detection of phospho-Akt1 (phosphorylated on Ser473) in cellular lysates using Alpha Technology.
Price Range : 1504.00 EUR - 16200.00 EUR
PerkinElmer

Membrane Target Systems: Serotonin 5HT7 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from CHO-K1 cells stably-transfected with human serotonin 5HT7 receptor, 400 units.
List Price : 784.00 EUR

Insulin (human, recombinant), [125I], 50 µCi

[125I]-Insulin (h) is suitable for the use in radioimmunoassay as well as receptor binding assay. [125I]-Insulin (h) is radioiodinated with no carrier added 125I using the LPO iodination procedure and is purified by reversed phase HPLC.
List Price : 2477.00 EUR
SureFire principle

AlphaScreen SureFire Phospho-AKT (Thr308) Kit

The AlphaScreen® SureFire® p-Akt1 (Thr308) assay is a sandwich immunoassay for quantitative detection of phospho-Akt1 (phosphorylated on Thr308) in cellular lysates using Alpha Technology.
Price Range : 1504.00 EUR - 16200.00 EUR
PerkinElmer

Membrane Target Systems: Vasopressin V1b (human) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from CHO-K1 cells stably-transfected with human Vasopressin V1b receptor, 400 units.
List Price : 784.00 EUR
PerkinElmer

Membrane Target Systems: Vasopressin V1b (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Vasopressin V1b receptor, in HEK-293 cells.
List Price : 784.00 EUR
Receptor-expressing cell lines

cAMPZen Frozen cells, Adenosine A1, Human Recombinant, CHO-K1

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 463.00 EUR
Receptor-expressing cell lines

AequoZen FroZen cells, Parental, 1321N1 (+Gα16)

AequoScreen Parental cell stably expressing the mitochondrially targeted apoaequorin gene. GPCRs of your choice can be transiently or stably transfected into these cell lines, for luminescence calcium assays.
List Price : 735.00 EUR
PerkinElmer

Membrane Target Systems: GABA B1b in HEK (human) membrane preparation, in HEK-293 cells. 400 Units.

Cell membranes prepared from HEK293 cells stably transfected with human GABA B1b receptor, 400 units.
List Price : 784.00 EUR
SureFire principle

AlphaScreen SureFire Monoclonal ERK p-T202/Y204, 50,000 Assay Points

The AlphaScreen® SureFire® Monoclonal p-ERK1/2 (Thr202/Tyr204) assay is a sandwich immunoassay for quantitative detection of phospho-ERK1/2 (phosphorylated on Thr202/Tyr204) in cellular lysates using Alpha Technology. This assay performs similarly to the TGRES SureFire kit, but contains a monoclonal antibody for phospho-ERK detection.
List Price : 17800.00 EUR
Receptor-expressing cell lines

Adenosine A1 AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
Receptor-expressing cell lines

AequoZen FroZen cells, Parental, HEK293 (+Gα16)

AequoScreen Parental cell stably expressing the mitochondrially targeted apoaequorin gene. GPCRs of your choice can be transiently or stably transfected into these cell lines, for luminescence calcium assays.
List Price : 735.00 EUR
Receptor-expressing cell lines

Adenosine A2A AequoScreen; cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
PerkinElmer

Membrane Target Systems: Vasopressin V1a (human) membrane preparation

Cell membranes prepared from cells stably-transfected with human Vasopressin V1a receptor, in HEK-293 cells.
List Price : 784.00 EUR

"GPCR" 1-50 of 118 Products and Services

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