PerkinElmer

CNS

OF

You'll gain the greatest possible insights into central nervous system targets and disorders -- in vitro, in situ, and in vivo – using our broad range of products for the neurologic researcher.

Assess mechanisms of central nervous system disease in biochemical, cellular, tissue, and animal models with our biomarker detection kits, cellular and in vivo imaging systems, and tissue pathology solutions, as well as our target-specific radiochemicals, radioligands, and receptor-transfected cell lines and cell membranes.

  • Accurately detect and quantitate biomarkers of central nervous system disease in cells, brain tissue homogenates, cerebrospinal fluid, and other sample types, using our fast, simple, pre-validated kits
  • Effectively study targeted binding using our radiolabeled ligands and steroids
  • Quantitate biomarkers in tissue samples through our industry-leading immunohistochemistry solutions
  • Probe the biological processes in animal models from molecular, functional, and anatomical perspectives with our in vivo imaging systems
  • Gain deeper insights from phenotypic analysis with our high content screening solutions

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Product Type
  • Accessories (34)
  • Consumables (3)
  • Reagents (165)
  • Software and Informatics (6)
Application
  • cAMP (11)
  • Drug Discovery & Development (46)
  • Immunohistochemistry (IHC) (23)
  • In situ hybridization (ISH) (23)
  • Molecular Biology (14)
  • Protein Analysis & Detection (24)
Assay Points
  • 10000 (5)
  • 500 (18)
  • 5000 (13)
Assay Target
  • Aβ oligomers (3)
  • Aβ1-40 (4)
  • Aβ1-42 (2)
  • Aβ1-x (1)
  • Aβ40 (3)
  • Aβ42 (1)
  • BDNF (2)
  • EPO (1)
  • Frataxin (2)
  • GAD67 (2)
  • Tau (1)
  • TDP-43 (2)
Assay Target Class
  • Cytokine (1)
  • GPCR (80)
  • Ion channel (3)
  • Peptide (13)
  • Protein (10)
Assay Validated
  • Binding (72)
  • Calcium Fluorescence (16)
  • Calcium Luminescence (32)
  • cAMP (20)
  • Downstream Phosphorylation (5)
  • GTPγS (19)
  • Inositol Phosphate (3)
Automation Compatible
  • Yes (24)
Buffer
  • Tricine (2)
  • Tricine with stabilizer and dye (12)
Concentration
  • 10 mCi/mL (10)
  • 12.5 mCi/mL (1)
Detection Method
  • Alpha (14)
  • Chromogenic (6)
  • Fluorescence (25)
  • Radiometric (15)
  • Time-Resolved Fluorescence (TRF) (10)
  • TR-FRET (10)
Experimental type
  • In vitro (24)
Fluorophore
  • Coumarin (1)
  • Cy3 (8)
  • Cy5 (4)
  • Fluorescein (6)
  • TMR (5)
Format
  • Microplates (24)
  • Slides (23)
Host Cell
  • 1321N1 (4)
  • CHO-K1 (65)
  • HEK293 (13)
  • L Cells (1)
  • UC11 (1)
Label Position
  • alpha (11)
  • gamma (3)
  • Nominally Labeled (1)
Nucleotide
  • ATP (3)
  • CTP (1)
  • dATP (2)
  • dCTP (2)
  • dTTP (1)
  • GTP (1)
  • UTP (4)
Product Brand Name
  • AequoScreen (14)
  • AequoZen (12)
  • AlphaLISA (14)
  • Ancillary Products (2)
  • cAMPZen (7)
  • EasyTide (7)
  • LANCE Ultra (10)
  • Membrane Target Systems (35)
  • NEN (2)
  • NEN Radiochemicals (6)
  • Opera (1)
  • Opera Phenix (7)
  • Operetta (29)
  • TSA (12)
  • TSA Plus (12)
  • ValiScreen (15)
Radionuclide
  • 33P (12)
  • 35S (2)
  • 3H (1)
Radioisotope
  • H-3 (1)
  • P-33 (12)
  • S-35 (2)
Receptor Type
  • 5-Hydroxytryptamine (Serotonin) (38)
  • Adrenergic (10)
  • Cannabinoid (9)
  • Dopamine (8)
  • GABA (4)
  • Galanin (10)
  • Neurotensin (4)
  • Nicotinic (4)
  • Opioid (11)
  • Tachykinin (1)
Target Species
  • Human (22)
  • Mouse (2)
Therapeutic Area
  • Angiogenesis (9)
  • Cardiovascular (37)
  • Central Nervous System (95)
  • CNS & Neurologic (1)
  • Diabetes (10)
  • Gastrointestinal (31)
  • Inflammation (51)
  • Metabolic (30)
  • Obesity (1)
  • Pain (21)
Volume
  • 0-50 (75)
  • 51-100 (8)
  • 201-250 (11)
  • 351-400 (32)
  • 451-500 (9)
  • Over 500 (9)
Volume Capacity
  • 150 µL (2)

"CNS" 1-50 of 208 Products and Services

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PerkinElmer

TSA Biotin System

TSA® biotin detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra biotin in the localized area of the probe or antibody.
Price Range : 452.00 EUR - 1506.00 EUR
TSA Cyanine 3 System/Cyanine 5 System

TSA Plus Cyanine 3 and Cyanine 5 System

TSA® Plus multi-fluorophore detection kit, for amplification of multiple signals in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols.
List Price : 938.00 EUR
PerkinElmer

TSA Plus DNP (HRP)

TSA® Plus DNP (HRP) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. The deposited DNP is detected using an anti-DNP hroseradish peroxidase, with appropriate substrate.
Price Range : 242.00 EUR - 432.00 EUR
PerkinElmer

Membrane Target Systems: Dopamine D1 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 784.00 EUR
Receptor-expressing cell lines

Nicotinic HM74a Aequoscreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
PerkinElmer

Membrane Target Systems: Serotonin 5HT6 (rat) membrane preparation

Cell membranes prepared from cells stably-transfected with rat Serotonin 5-HT6 receptor, in HEK-293 cells.
List Price : 784.00 EUR
AlphaLISA immunoassay kits
Price Range : 2765.00 EUR - 21600.00 EUR
PerkinElmer

TSA Cyanine 3 Reagent Pack

TSA® Cyanine 3 (Cy3) reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.
Price Range : 463.00 EUR - 2170.00 EUR

Frataxin (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human Frataxin Detection Kit is designed for detection and quantitation of human frataxin in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 802.00 EUR - 10700.00 EUR
TSA Coumarin System (100-300 slides)

TSA Coumarin System, for 100-300 Slides

TSA® coumarin detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra coumarin in the localized area of the probe or antibody.
List Price : 1017.00 EUR
Receptor-expressing cell lines

Serotonin 5-HT1A, Human Recombinant, CHO-K1 cAMPZen Frozen cells

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 463.00 EUR

Amyloid β 1-40 (high specificity) (human) AlphaLISA Detection Kit

The AlphaLISA® Human Amyloid beta 1-40 (Aß 1-40) (high specificity) Detection Kit is designed for detection and quantitation of human Aß 1-40 in cerebrospinal fluid (CSF), buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 2934.00 EUR - 22900.00 EUR
Receptor-expressing cell lines

cAMPZen Frozen cells, Nicotinic HM74a (GPR109A), Human Recombinant, CHO-K1

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 463.00 EUR
TSA Cyanine 3 & 5, TMR, Fluorescein Evaluation Kit

TSA Cy 3, Cy 5, TMR, Fluorescein Evaluation Kit

TSA® Plus multi-fluorophore detection kit, for amplification of multiple signals in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols.
List Price : 427.00 EUR

dATP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Deoxyadenosine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 592.00 EUR - 2446.00 EUR
Receptor-expressing cell lines

Adrenergic alpha 2A AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.

Aβ 1-40 (human) High Specificity AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human Aβ40 enables the detection and quantitation of human Aβ40 in human cerebrospinal fluid and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps). The assay shows negligible cross-reactivity with other forms of Amyloid beta (i.e. Aβ1-38 and Aβ1-42).
Price Range : 2849.00 EUR - 22200.00 EUR
PerkinElmer

TSA Plus Fluorescein

TSA® Plus fluorescein detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra fluorescein in the localized area of the probe or antibody.
Price Range : 298.00 EUR - 2380.00 EUR

dCTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Deoxycytidine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 523.00 EUR - 2993.00 EUR
PerkinElmer

Membrane Target Systems: Galanin Gal2 (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 784.00 EUR
Receptor-expressing cell lines

Dopamine D2L AequoScreen Cell Line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.

ATP, [γ-33P]- 3000Ci/mmol, 10mCi/ml

Adenosine triphosphate, labeled on the gamma phosphate group with 33P.
Price Range : 479.00 EUR - 2156.00 EUR
Receptor-expressing cell lines

ValiScreen Serotonin 5HT-2C (e) (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
Receptor-expressing cell lines

5-Hydroxytryptamine 5-HT3A (Serotonin) AequoScreen Cell Line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
PerkinElmer

Membrane Target Systems: Serotonin 5HT1a (human) membrane preparation, in CHO-K1 cells. 400 Units.

Cell membranes prepared from cells stably-transfected with human serotonin 5HT1a receptor
List Price : 784.00 EUR
AlphaLISA immunoassay kits

Amyloid ß 1-x (human) AlphaLISA Detection Kit

The AlphaLISA® Human Amyloid beta 1-x (Aß 1-x) Detection Kit is designed for detection and quantitation of human Aß 1-x in cerebrospinal fluid (CSF), buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 2934.00 EUR - 22900.00 EUR
Receptor-expressing cell lines

AequoZen Frozen cells, Serotonin 5-HT2A, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 735.00 EUR
Receptor-expressing cell lines

Opioid Mu (OP3) (human) ValiScreen cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
AlphaLISA immunoassay kits

Amyloid β 1-42 (high specificity) (human) AlphaLISA Detection Kit

The AlphaLISA® Human Amyloid beta 1-42 (Aß 1-42) (high specificity) Detection Kit is designed for detection and quantitation of human Aß 1-42 in cerebrospinal fluid (CSF), buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 2934.00 EUR - 22900.00 EUR
Receptor-expressing cell lines

ValiScreen Nicotinic HM74a (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.

dCTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Deoxycytidine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 572.00 EUR - 3028.00 EUR
Receptor-expressing cell lines

Adrenergic alpha 2B AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
Amplification Diluent

TSA Tetramethylrhodamine Tyramide Reagent Pack, Reagents for 100-300 Slides

TSA® tetramethylrhodamine (TMR) reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.
List Price : 812.00 EUR

ATP, [γ-33P]- 3000Ci/mmol, 10mCi/ml

Adenosine triphosphate, labeled on the gamma phosphate group with 33P.
Price Range : 792.00 EUR - 2124.00 EUR
PerkinElmer

TSA Fluorescein System

TSA® fluorescein detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra fluorescein in the localized area of the probe or antibody.
Price Range : 579.00 EUR - 1017.00 EUR
PerkinElmer

TSA Biotin Reagent Pack

TSA® biotin reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.
Price Range : 1202.00 EUR - 3943.00 EUR
PerkinElmer

Membrane Target Systems: Serotonin 5HT-2A (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 784.00 EUR
Receptor-expressing cell lines

AequoZen Frozen cells, Adrenergic α2B, Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 735.00 EUR
AlphaLISA immunoassay kits

AlphaLISA Two-in-One Detection Kit: Total or Oligomerized Aβ42

The AlphaLISA® Two-in-One Amyloid Beta 42 (Aβ 1-42) Detection Kit is designed for detection and quantitation of total and oligomerized human Aβ 1-42 in cell culture supernatants and cerebrospinal fluid (CSF) using a homogeneous (no-wash steps, no separation steps) assay. The kit includes standards for both oligomerized and monomeric Aβ1-42, allowing the assay to be run for accurate quantitation. The oligomerized form is provided in collaboration with Crossbeta, using their innovative oligomer stabilization technology. 
Protein

Frataxin (human), lyophilized (LANCE)

Human Frataxin standard, lyophilized, for use in running standard curves in LANCE TR-FRET no-wash detection assays. This standard is already provided in the LANCE Ultra Human Frataxin TR-FRET Detection Kit, but can be ordered separately.
List Price : 242.00 EUR
Receptor-expressing cell lines

ValiScreen Dopamine D3 (human) cell line

Our stable recombinant ValiScreen cell lines express a variety of GPCRs for binding and functional assays.
TSA -Plus DIG, 50-150 slides

TSA Plus DIG Evaluation Kit

TSA® Plus DIG detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra DIG in the localized area of the probe or antibody.
Price Range : 204.00 EUR - 1349.00 EUR
Receptor-expressing cell lines

Galanin Gal1 AequoScreen cell line

Our stable recombinant AequoScreen cell lines express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light.
Receptor-expressing cell lines

Cannabinoid CB1, Human Recombinant, CHO-K1 cAMPZen® Frozen cells

Our frozen, irradiated cAMPZen cells express a variety of GPCRs for binding and functional assays. No cell culture is required prior to testing.
List Price : 463.00 EUR
PerkinElmer

TSA Plus Biotin

TSA® Plus Biotin detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra biotin in the localized area of the probe or antibody.
Price Range : 359.00 EUR - 1349.00 EUR

UTPαS, [35S]- 1250Ci/mmol, 12.5mCi/ml

Uridine triphosphate, labeled on the alpha phosphate group with 35S.
Price Range : 531.00 EUR - 1313.00 EUR
PerkinElmer

Membrane Target Systems: Serotonin 5HT-2C (e) (human) membrane preparation, in CHO-K1 cells. 400 Units.

Our Membrane Target System membranes are prepared from cells that express recombinant or endogenous receptors. Selected for optimal performance in binding assays.
List Price : 784.00 EUR
Receptor-expressing cell lines

AequoZen Frozen cells, Serotonin 5-HT5A Human Recombinant, CHO-K1

Our frozen, irradiated AequoZen cells express a variety of GPCRs which all couple to a calcium response. Upon GPCR stimulation and subsequent calcium binding to the aequorin oxidation of coelenterazine leads to emission of light. No cell culture is required prior to testing, for these frozen cells.
List Price : 735.00 EUR

Amyloid β 1-42 (mouse/rat) AlphaLISA Detection Kit

The AlphaLISA® Mouse/Rat Amyloid beta (Aß 1-42) Detection Kit is designed for detection and quantitation of mouse or rat Aß 1-42 in serum, cerebrospinal fluid (CSF), buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 2934.00 EUR - 22900.00 EUR

CTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Cytidine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 501.00 EUR - 2688.00 EUR

"CNS" 1-50 of 208 Products and Services

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