PerkinElmer

Cancer Immunotherapy & Immunology

OF

Immuno-oncology has emerged as an exciting area of personalized medicine because of its tremendous potential to harness the powerful immune system to target and destroy cancer cells with few side effects, when targeted to the right tumor at the right time. Researchers are exploring the complex relationship between tumor cells and the immune system within the tumor microenvironment in order to discover new immuno-oncology targets and therapies.

Research Tools

Our cancer immunotherapy research solutions span the entire drug discovery workflow, from drug screening to studies in pre-clinical animal models to imaging of human tumor samples in clinical trials.

  • Immunoassays and reagents
  • Plate readers
  • Advanced multiplex tissue staining kits
  • Image analysis software
  • Quantitative pathology imaging systems
  • High content imaging and analysis
  • In Vivo imaging
  • Contract services

Kits and Reagents for Immuno-Oncology Research

Targeting immune checkpoint inhibitors, such as PD-1, PD-L1, and CTLA-4, has become pivotal in immunotherapy research, and so have monoclonal antibodies (mAbs), whether naked or conjugated with a chemotherapy agent or radioactive particle. Another area of active investigation is chimeric antigen receptor (CAR) T-cell therapy, where T cells are genetically programmed to attach to proteins on the surface of cancer cells. We offer a number of reagent technologies, radioactive and non-rad, for detection of key immuno-oncology targets.
Vectra 3 200 slide
Vectra 3 200 slide

Instrumentation for Immuno-Oncology Research

With our full suite of immuno-oncology products and solutions––including instrumentation and software for in vitro, ex vivo and in vivo models––we enable rapid and targeted discoveries in cancer immunotherapy.
Contract Research Services for Phenotyping In Situ
Contract Research Services for Phenotyping In Situ

Contract Services for Immuno-Oncology Research

Looking for an assay that’s not commercially available? Ask us about our custom services for immuno-oncology research including custom labeling of biomolecules, full assay development and transfer, and tissue imaging and analysis.
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"Cancer Immunotherapy & Immunology" 1-50 of 307 Products and Services

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IVIS SpectrumBL High Throughput Optical Imaging System

IVIS Spectrum In Vivo Imaging System

The IVIS® Spectrum in vivo imaging system uses a novel patented optical imaging technology to facilitate non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
IVIS SpectrumBL High Throughput Optical Imaging System

IVIS SpectrumBL High-Throughput In Vivo Optical Imaging System

The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
Quantum GX microCT Imaging System

Quantum GX microCT Imaging System

With microCT imaging systems, speed and resolution are usually a two-system tradeoff – until now. Gain a better understanding of disease and its progression with combined high-speed, low-dose x-ray, and high-resolution microCT imaging in one instrument.
 
Vectra Polaris with monitor

Vectra Polaris Automated Quantitative Pathology Imaging System

The Vectra® Polaris Automated Quantitative Pathology Imaging System integrates both multispectral imaging and automated slide scanning to better visualize, analyze, quantify, and phenotype immune cells in situ in FFPE tissue sections and TMAs.
IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina III In Vivo Imaging System

The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
G8 PET/CT benchtop scanner for preclinical imaging research

G8 PET/CT Preclinical Imaging System

Ultrasensitive and fast multimodal preclinical PET/CT imaging at your benchtop. The G-Platform offers Full Solutions for PET Imaging  and includes the G4 and G8 imaging systems.
Mantra benchtop

Mantra Quantitative Pathology Workstation

Mantra quantitative pathology workstation with inForm® image analysis software enables easy visualization, quantification and phenotyping of multiple types of immune cells simultaneously in intact FFPE tissue sections for cancer immunology research.
IVIS SpectrumCT 2D/3D Optical/CT In Vivo Imaging System

IVIS SpectrumCT In Vivo Imaging System

The IVIS® SpectrumCT preclinical in vivo imaging system expands upon the versatility and advanced optical feature sets of the IVIS platform integrated with low dose microCT to support longitudinal imaging.
Vectra image

Vectra 3.0 Automated Quantitative Pathology Imaging System

The Vectra® 3 automated quantitative pathology imaging system accurately detects and measures weakly expressing and overlapping biomarkers within a single H&E, IHC or IF intact FFPE tissue section or TMA.

Opera Phenix High-Content Screening System

The Opera Phenix™ High Content Screening System is the premier confocal solution for today's most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera® High Content Screening System, the Opera Phenix is designed for high-throughput, phenotypic screening and assays involving complex disease models, such as live cells, primary cells and microtissues.
G4 Preclinical PET benchtop scanner with integrated X-ray

G4 PET/X-ray Preclinical Imaging System

Ultrasensitive and fast multimodal PET/X-ray imaging at your benchtop. The G-Platform offers and includes the G4 and G8 imaging systems.
IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina LT In Vivo Imaging System

The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

IVIS Lumina XRMS In Vivo Imaging System

Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.

Operetta High-Content Imaging System

As scientists grapple with increasingly complex biological questions, they need to conduct larger, more complex imaging experiments. So they’re turning to the Operetta® High Content Imaging System – the ideal solution for analyzing the inner workings of healthy and diseased cells.
 
Operetta CLS High Content Analysis Instrument

Operetta CLS High-Content Analysis System

Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS™ high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS™ lets you find even subtle phenotypic changes.
AlphaLISA immunoassay kits

BCL-2 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for BCL-2 enables the detection and quantitation of human BCL-2 in serum, buffered solution, or cell culture medium using a homogeneous AlphaLISA assay (no wash steps). This kit is not cross reactive with mouse Bcl-2.
Price Range : 627.00 EUR - 20400.00 EUR
AlphaLisa Analyte 2

α-tubulin standard, liquid (AlphaLISA)

Human α-tubulin standard, liquid, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA α-tubulin Detection Kit, but can be ordered separately.
List Price : 429.00 EUR
AlphaLISA immunoassay kits

Fibronectin (human plasma) AlphaLISA Detection Kit

The AlphaLISA® Human Plasma Fibronectin Detection Kit is designed for detection and quantitation of human plasma fibronectin (hFN) in human serum, plasma, and, cell lysate, cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 449.00 EUR - 9800.00 EUR
AlphaLISA immunoassay kits

α-tubulin AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for α-tubulin enables the detection and quantitation of human α-tubulin in tissue homogenates and cell lysates using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 702.00 EUR - 19700.00 EUR
AlphaLISA immunoassay kits

AlphaLISA Human Programmed Cell Death Protein 1 (PD-1) Detection Kit

The AlphaLISA® Human PD-1 Detection Kit is designed for detection and quantitation of Human Programmed Cell Death Protein 1 (PD-1) in human serum, plasma, and cell culture supernatants using a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 650.00 EUR - 10100.00 EUR
AlphaLisa Analyte 2

MMP-7 (human), lyophilized (AlphaLISA)

Human MMP-7 standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Human MMP7 Detection Kit, but can be ordered separately.
List Price : 242.00 EUR
AlphaLISA assay principle

BMP-9 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human BMP-9 enables the quantitative determination of human Bone Morphogenetic Protein 9 (BMP-9) in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 604.00 EUR - 18100.00 EUR
Bioware U87 Glioblastoma Bioluminescent Oncology Cell Line

Bioware® Brite Cell Line U87 MG-Red-FLuc

Our bioluminescent light-producing oncology cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP) for in vivo studies.
AlphaLISA immunoassay kits

Factor VIII (human) AlphaLISA Biotin-Free Detection Kit

The AlphaLISA® Human BDNF Biotin-Free Detection Kit is designed for the quantitative detection of human Brain Derived Neurotrophic Factor (BDNF) in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit is compatible with high-biotin culture media and other sample types that contain high levels biotin.
Price Range : 462.00 EUR - 10100.00 EUR
AlphaLISA immunoassay kits

CD276 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human CD276 enables the quantitative determination of human Cluster of Differentiation 276 (CD276, B7-H3) in serum, buffered solution, and cell culture media using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 756.00 EUR - 14500.00 EUR

dTTP, [α-33P]- 3000Ci/mmol, 10mCi/ml, 1 mCi

Deoxythymidine triphosphate, labeled on the alpha phosphate group with 33P.
List Price : 2993.00 EUR
Assay principle for LANCE TR-FRET binding assay

CTLA4-CD80 AlphaLISA Binding Kit

This kit is designed for the detection of binding activity between Human CTLA-4 and CD80, using a homogeneous AlphaLISA assay (no wash steps). This assay can facilitate the design and development of antibody therapetics by using competitive binding to CTLA-4/CD80.
Price Range : 1813.00 EUR - 11000.00 EUR
Bioware Bioluminescent Oncology Cell LInes

Bioware® Brite Cell Line MCF7 Red-FLuc

Our bioluminescent light-producing oncology cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP) for in vivo studies.
AlphaLISA immunoassay kits

CXCL11 (human) AlphaLISA Detection Kit

The AlphaLISA® Chemokine (C-X-C motif) ligand 11 (CXCL11) Detection Kit is designed for detection and quantitation of Human Chemokine (C-X-C motif) ligand 11 (CXCL11) in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1532.00 EUR - 10200.00 EUR
AlphaLISA immunoassay kits

PTEN (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human PTEN enables the detection and quantitation of human PTEN in tissue homogenates and cell lysates using a homogeneous AlphaLISA assay (no wash steps). Other species of PTEN were not tested, but detection is expected with mouse and rat PTEN due to >99% sequence homology.
Price Range : 462.00 EUR - 10100.00 EUR
AlphaLisa Analyte 2

PTEN (human), lyophilized (AlphaLISA)

Human PTEN standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Human PTEN Detection Kit, but can be ordered separately.
List Price : 249.00 EUR
Protein

COX-2 (human), liquid (LANCE)

Human COX-2 standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Human COX-2 TR-FRET Detection Kit, but can also be ordered separately.
List Price : 298.00 EUR
AlphaLISA immunoassay kits

COX-2 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human COX-2 enables the detection and quantitation of human COX-2 in cell culture supernatants and cell extracts using a homogeneous AlphaLISA assay (no wash steps). The assay shows no cross-reactivity with human COX-1 nor with sheep COX-2.
Price Range : 4256.00 EUR - 31500.00 EUR
In vivo Fluorescent Agents

OsteoSense 680EX Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
List Price : 435.00 EUR
Opal 4-Color Automation IHC Kit 50 slides - NEL800001KT

Opal Automation IHC Kit 50 slides

Opal is a practical workflow for the simultaneous detection of up to six tissue biomarkers plus nuclear counterstain within a single image. The method is similar to standard immunohistochemistry (IHC) and is accessible to many laboratories where standard IHC method development is performed.
Price Range : 753.00 EUR - 996.00 EUR

PD-1 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human PD-1 Detection Kit is designed for detection and quantitation of human PD-1 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 779.00 EUR - 10400.00 EUR
AlphaLISA immunoassay kits

Trefoil factor 3 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Trefoil Factor 3 (TFF3) Detection Kit is designed for detection and quantitation of human TFF3 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1532.00 EUR - 10200.00 EUR

MMP-3 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human MMP-3 Detection Kit is designed for detection and quantitation of human matrix metalloproteinase-3 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 802.00 EUR - 10700.00 EUR
AlphaLISA immunoassay kits

TGF-β1 (human) AlphaLISA Biotin-Free Detection Kit

The AlphaLISA® Human TGF-β1 Biotin-Free Detection Kit is designed for the quantitative detection of human TGF-β1 in serum, cell culture medium, and other samples types using a homogeneous (no wash steps, no separation steps) assay. The biotin-free kit is compatible with high-biotin culture media and other sample types that contain high levels biotin.
Price Range : 449.00 EUR - 9800.00 EUR
Bioware Bioluminescent Oncology Cell LInes

Bioware® Brite Cell Line NCI-H460 Red-FLuc

Our bioluminescent light-producing oncology cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP) for in vivo studies.

CTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Cytidine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 501.00 EUR - 2688.00 EUR
TSA -Plus Tetramethylrhodamine System

TSA Plus TMR

TSA® Plus tetramethylrhodamine (TMR) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra TMR in the localized area of the probe or antibody.
Price Range : 543.00 EUR - 2380.00 EUR

Mannose, D-[2-3H(N)]-, Specific Activity: 15-30Ci (555GBq-1.11TBq)/mmol, 5mCi (185MBq)

5 mCi quantities of D-[2-3H(N)]-Mannose are available for your research.
List Price : 2146.00 EUR
PerkinElmer

TSA Cyanine 3 Reagent Pack

TSA® Cyanine 3 (Cy3) reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.
Price Range : 463.00 EUR - 2170.00 EUR
TSA -Plus Cyanine 5 System

TSA Plus Cyanine 5

TSA® Plus Cyanine 5 (Cy5) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy5 in the localized area of the probe or antibody.
Price Range : 298.00 EUR - 2380.00 EUR
PerkinElmer

TSA Plus Cyanine 3

TSA® Plus Cyanine 3 (Cy3) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy3 in the localized area of the probe or antibody.
Price Range : 298.00 EUR - 2380.00 EUR
AlphaLisa Analyte 2

EGFR (human), lyophilized (AlphaLISA)

Human EGFR standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA EGFR kit, but can be ordered separately.
List Price : 249.00 EUR
AlphaLisa Analyte 2

Laminin (human), lyophilized (AlphaLISA)

Human laminin standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Human Laminin Detection Kit, but can be ordered separately.
List Price : 242.00 EUR
Bioluminescent Oncology Cell Lines - Bioware

Bioware® Brite Cell Line K562 Red-FLuc

Our bioluminescent light-producing oncology cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP) for in vivo studies.
In vivo Fluorescent Agents

OsteoSense 750EX Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
List Price : 435.00 EUR

"Cancer Immunotherapy & Immunology" 1-50 of 307 Products and Services

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